8.04324

1,1,1,3,3,3-Hexamethyldisilazane

for synthesis

• Synonym(s): 1,1,1,3,3,3-Hexamethyldisilazane, Bis(trimethylsilyl)amine, HMDS
• Empirical Formula (Hill Notation): C₆H₁₉NSi₂
• CAS Number: 999-97-3
• Molecular Weight: 161.39
• MDL number: MFCD00008259
• UNSPSC Code: 12352103
• EC Index Number: 213-668-5
• NACRES: NA.22

Properties

• vapor pressure: 20 hPa ( 20 °C)
• Quality Level: 200
• Assay: ≥98% (GC)
• form: liquid
• autoignition temp.: 325 °C
• potency: 847 mg/kg LD₅₀, oral (Rat); 550 mg/kg LD₅₀, skin (Rabbit)
• expl. lim.: 0.8-25.9 % (v/v)
• kinematic viscosity: 0.9 cSt(25 °C)
• bp: 126 °C/1013 mbar
• mp: -82 °C
• transition temp: flash point 15 °C
• density: 0.78 g/cm³ at 20 °C
• storage temp.: 2-30°C
• InChI: 1S/C6H19NSi2/c1-8(2,3)7-9(4,5)6/h7H,1-6H3
• InChI key: FFUAGWLWBBFQJT-UHFFFAOYSA-N

Description

Application

• Handling and Safety Protocols of 1,1,1,3,3,3-Hexamethyldisilazane: This article presents a comprehensive overview of the handling and safety protocols associated with 1,1,1,3,3,3-Hexamethyldisilazane, emphasizing its applications in various industrial and pharmaceutical contexts. The study provides insights on its safe usage, particularly focusing on its role as a silylation agent in analytical chemistry and as a precursor in chemical vapor deposition processes (Toxicol Ind Health, 2019).

Analysis Note

Assay (GC, area%): ≥ 98 %
Density (d 20 °C/ 4 °C): 0.774 - 0.775
Identity (IR): passes test

Safety Information

• Pictograms: GHS02,GHS06
• Signal Word: Danger
• Hazard Statements: H225 - H302 + H332 - H311 - H412
• Precautionary Statements: P210 - P273 - P280 - P301 + P312 - P303 + P361 + P353 - P304 + P340 + P312
• Hazard Classifications: Acute Tox. 3 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Flam. Liq. 2
• Storage Class Code: 3 - Flammable liquids
• WGK: WGK 2
• Flash Point(F): 52.5 °F - closed cup
• Flash Point(C): 11.4 °C - closed cup