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Merck
  • Flap prefabrication using high-density porous polyethylene in an animal model – an experimental study.

Flap prefabrication using high-density porous polyethylene in an animal model – an experimental study.

Medical science monitor basic research (2013-08-22)
Łukasz Krakowxzyk, Adam Maciejewski, Cezary Szymczyk, Maciej Grajek, Ewa Stobiecka, Stanisław Pòłtorak
摘要

The search for new surgical flap techniques and modifications of already existing ones is gaining increasing popularity. Progress in flap designing and harvesting have improved the functional and aesthetic results, especially in head and neck reconstruction. Ten pigs were used in this study. In the first operation, high-density porous polyethylene prefabrication was performed bilaterally in all pigs. After 8 weeks, each prefabricated complex was explored, resected, and macroscopically evaluated. All of 20 prefabricated flaps survived. No serious surgical complications were observed. In 2 cases there was chronic inflammation and in 4 cases there was instability of the implant. After this experimental study, we believe that the use of high-density porous polyethylene in flap prefabrication may be a good option for reconstruction of 3-dimensional defects, especially in patients with limited donor tissues.

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Sigma-Aldrich
聚乙烯, Ultra-high molecular weight, surface-modified, powder, 34-50 μm particle size
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聚乙烯, average Mw ~4,000 by GPC, average Mn ~1,700 by GPC
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聚乙烯, low density, melt index 25 g/10 min (190°C/2.16kg)
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聚乙烯, Ultra-high molecular weight, average Mw 3,000,000-6,000,000
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聚乙烯, High density, melt index 12 g/10 min (190 °C/2.16kg)
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聚乙烯, Medium density
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聚乙烯, Linear low density, melt index 1.0 g/10 min (190°C/2.16kg)
Sigma-Aldrich
聚乙烯, Ultra-high molecular weight, surface-modified, powder, 125 μm avg. part. size
Sigma-Aldrich
聚乙烯, High density, melt index 2.2 g/10 min (190 °C/2.16kg)
聚乙烯 (LDPE), ERM®, certified reference material
Supelco
聚乙烯, analytical standard, for GPC, 2,000