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V900919

Sigma-Aldrich

两性霉素B 来源于链霉菌 属

suitable for cell culture, Vetec™, BioReagent

别名:

两性霉素B 来源于链霉菌 属, Fungizone

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About This Item

经验公式（希尔记法）:
C47H73NO17
CAS号:
1397-89-3
分子量:
924.08
Beilstein:
78342
EC號碼:
215-742-2
MDL號碼:
MFCD00877763
分類程式碼代碼:
12352207
PubChem物質ID:
329830225

product name

两性霉素B 来源于链霉菌 属, Vetec™, reagent grade, BioReagent, suitable for cell culture, ~80%

等級

reagent grade

品質等級

100

產品線

BioReagent
Vetec™

化驗

~80%

技術

cell culture | mammalian: suitable

抗生素活性譜

fungi
yeast

作用方式

cell membrane | interferes

儲存溫度

2-8°C

SMILES 字串

C[C@H]1O[C@@H](O[C@@H]2C[C@@H]3O[C@](O)(C[C@@H](O)C[C@@H](O)[C@H](O)CC[C@@H](O)C[C@@H](O)CC(=O)O[C@@H](C)[C@H](C)[C@H](O)[C@@H](C)\C=C\C=C\C=C\C=C\C=C\C=C\C=C\2)C[C@H](O)[C@H]3C(O)=O)[C@@H](O)[C@@H](N)[C@@H]1O

InChI

1S/C47H73NO17/c1-27-17-15-13-11-9-7-5-6-8-10-12-14-16-18-34(64-46-44(58)41(48)43(57)30(4)63-46)24-38-40(45(59)60)37(54)26-47(61,65-38)25-33(51)22-36(53)35(52)20-19-31(49)21-32(50)23-39(55)62-29(3)28(2)42(27)56/h5-18,27-38,40-44,46,49-54,56-58,61H,19-26,48H2,1-4H3,(H,59,60)/b6-5+,9-7+,10-8+,13-11+,14-12+,17-15+,18-16+/t27-,28-,29-,30+,31+,32+,33-,34-,35+,36+,37-,38-,40+,41-,42+,43+,44-,46-,47+/m0/s1

InChI 密鑰

APKFDSVGJQXUKY-INPOYWNPSA-N

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相关类别

生化／生理作用

两性霉素B可与甾醇结合，在膜中形成孔，并导致小分子的泄漏。该产品对真菌和酵母最有效。
两性霉素B可用于急性侵袭性真菌感染的初级治疗，例如曲霉菌病。

法律資訊

Vetec is a trademark of Merck KGaA, Darmstadt, Germany

象形圖

Health hazard
GHS08

訊號詞

Danger

危險聲明

H372

危險分類

STOT RE 1

儲存類別代碼

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

水污染物質分類（WGK）

WGK 3

閃點（°F）

Not applicable

閃點（°C）

Not applicable

分析证书(COA)

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White MH, et al.
Clinical Infectious Diseases, 27(2), 296-302 (1998)
Voriconazole versus amphotericin B for primary therapy of invasive aspergillosis.
Herbrecht R, et al.
The New England Journal of Medicine, 347(6), 408-415 (2002)
Malav S Trivedi et al.
The Journal of nutritional biochemistry, 25(10), 1011-1018 (2014-07-16)
Dietary interventions like gluten-free and casein-free diets have been reported to improve intestinal, autoimmune and neurological symptoms in patients with a variety of conditions; however, the underlying mechanism of benefit for such diets remains unclear. Epigenetic programming, including CpG methylation
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The use of ion radiation therapy is growing due to the continuously increasing positive clinical experience obtained. Therefore, there is a high interest in radio-biological experiments comparing the relative efficiency in cell killing of ions and photons as photons are
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Because there are currently no reliable predictors for progression of ductal carcinoma in situ (DCIS) to invasive disease, nearly all patients receive comprehensive therapy, leading to over-treatment in many cases. Few in vitro models for studying DCIS progression have been
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