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1172006

USP

地昔帕明 盐酸盐

United States Pharmacopeia (USP) Reference Standard

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About This Item

经验公式（希尔记法）:
C18H22N2 · HCl
CAS号:
58-28-6
分子量:
302.84
MDL號碼:
MFCD00058108
分類程式碼代碼:
41116107
PubChem物質ID:
329749539
NACRES:
NA.24

等級

pharmaceutical primary standard

API 家族

desipramine

製造商／商標名

USP

應用

pharmaceutical (small molecule)

形式

neat

SMILES 字串

Cl[H].CNCCCN1c2ccccc2CCc3ccccc13

InChI

1S/C18H22N2.ClH/c1-19-13-6-14-20-17-9-4-2-7-15(17)11-12-16-8-3-5-10-18(16)20;/h2-5,7-10,19H,6,11-14H2,1H3;1H

InChI 密鑰

XAEWZDYWZHIUCT-UHFFFAOYSA-N

基因資訊

human ... SLC6A2(6530)

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相关类别

一般說明

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

應用

Desipramine hydrochloride USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:
  • Clomipramine Hydrochloride
  • Desipramine Hydrochloride
  • Desipramine Hydrochloride Tablets
  • Imipramine Hydrochloride
  • Imipramine Hydrochloride Tablets
  • Imipramine Pamoate Capsules

分析報告

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

其他說明

Sales restrictions may apply.

象形圖

Health hazardExclamation mark
GHS08,GHS07

訊號詞

Danger

危險分類

Acute Tox. 4 Oral - Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3

標靶器官

Respiratory system

儲存類別代碼

11 - Combustible Solids

水污染物質分類（WGK）

WGK 3

閃點（°F）

Not applicable

閃點（°C）

Not applicable

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分析证书(COA)

Lot/Batch Number

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Aaron Kucinski et al.
Behavioural brain research, 282, 155-164 (2015-01-18)
Falls in patients with Parkinson's disease (PD) are a major and levodopa-unresponsive source of morbidity. We previously described an animal model of falls resulting from impairments in attentional-motor interactions. Reproducing the multisystem dopaminergic-cholinergic cell loss in patients with a history
Fiona B Carr et al.
Molecular pain, 10, 39-39 (2014-06-21)
Descending control of nociceptive processing, by pathways originating in the rostral ventromedial medulla (RVM) and terminating in the dorsal horn, contributes to behavioural hypersensitivity in a number of pain models. Two facilitatory pathways have been identified and are characterized by
Andre Der-Avakian et al.
Biological psychiatry, 76(7), 542-549 (2014-03-01)
Anhedonia, or diminished interest or pleasure in rewarding activities, characterizes depression and reflects deficits in brain reward circuitries. Social stress induces anhedonia and increases risk of depression, although the effect of social stress on brain reward function is incompletely understood.
Edgardo Falcon et al.
Psychopharmacology, 232(5), 907-915 (2014-09-03)
Buprenorphine (BPN) has been shown to rapidly improve mood in treatment-resistant depressed patients in small clinical studies. However, BPN's effects in preclinical tests for mood and antidepressant efficacy are largely unexplored. The current study examined the effects of BPN in
Sylvia Navailles et al.
CNS neuroscience & therapeutics, 20(7), 671-678 (2014-04-30)
Serotonin (5-HT) neurons mediate the ectopic release of dopamine (DA) induced by L-DOPA in the Parkinsonian brain. We hypothesized that the participation of noradrenalin transporters (NET) in the clearance of DA may account for the lower effect of L-DOPA in
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