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Merck

1001502

USP

乙酰丙嗪 马来酸盐

United States Pharmacopeia (USP) Reference Standard

别名:

2-乙酰基-10-(3-二甲基氨基丙基)吩噻嗪 马来酸盐, 乙酰丙嗪 马来酸盐

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About This Item

经验公式(希尔记法):
C19H22N2OS · C4H4O4
CAS号:
分子量:
442.53
MDL號碼:
分類程式碼代碼:
41116107
PubChem物質ID:
NACRES:
NA.24

等級

pharmaceutical primary standard

API 家族

acepromazine

製造商/商標名

USP

應用

pharmaceutical (small molecule)

格式

neat

SMILES 字串

OC(=O)\C=C/C(O)=O.CN(C)CCCN1c2ccccc2Sc3ccc(cc13)C(C)=O

InChI

1S/C19H22N2OS.C4H4O4/c1-14(22)15-9-10-19-17(13-15)21(12-6-11-20(2)3)16-7-4-5-8-18(16)23-19;5-3(6)1-2-4(7)8/h4-5,7-10,13H,6,11-12H2,1-3H3;1-2H,(H,5,6)(H,7,8)/b;2-1-

InChI 密鑰

FQRHOOHLUYHMGG-BTJKTKAUSA-N

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一般說明

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

應用

Acepromazine maleate USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:
  • Acepromazine Maleate Injection
  • Acepromazine Maleate Tablets

生化/生理作用

乙酰丙嗪是一种吩噻嗪类抗精神病药,仅用作兽药(马、狗和猫)。该化合物是抗精神病药物氯丙嗪(#C8138)的类似物。该药物被认为可以阻断大脑中的多巴胺受体。最近发现该化合物抑制 ABCG2 转运蛋白,该蛋白在肿瘤中的过表达与耐药性有关。

分析報告

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

其他說明

Sales restrictions may apply.

相關產品

象形圖

Skull and crossbones

訊號詞

Danger

危險聲明

防範說明

危險分類

Acute Tox. 3 Oral - STOT SE 3

標靶器官

Central nervous system

儲存類別代碼

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

水污染物質分類(WGK)

WGK 1

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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Journal of the American Association for Laboratory Animal Science : JAALAS, 53(5), 494-501 (2014-09-26)
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Metabolism: clinical and experimental, 64(2), 330-337 (2014-12-04)
Insulin injected directly into skeletal muscle diffuses rapidly through the interstitial space to cause glucose uptake, but this is blocked in insulin resistance. As glucotoxicity is associated with endothelial dysfunction, the observed hyperglycemia in diet-induced obese dogs may inhibit insulin
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Pulmonary pharmacology & therapeutics, 28(2), 114-121 (2014-06-15)
This study characterised the in vitro and in vivo profiles of two novel long-acting muscarinic antagonists, aclidinium bromide and glycopyrronium bromide, using tiotropium bromide and ipratropium bromide as comparators. All four antagonists had high affinity for the five muscarinic receptor sub-types (M1-M5);
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The use of xenobiotic compounds in animal husbandry has given rise to consumer anxieties regarding residual risk and food safety. Thus, animal tissues have become main samples for residue analysis and food safety for sedatives. In this study, a rapid

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