跳转至内容
Merck
所有图片(2)

文件

WH0006925M2

Sigma-Aldrich

Monoclonal Anti-TCF4 antibody produced in mouse

clone 1F6, purified immunoglobulin, buffered aqueous solution

别名:

Anti-E22, Anti-ITF2, Anti-SEF2, Anti-SEF21, Anti-SEF21A, Anti-SEF21B, Anti-transcription factor 4

登录查看公司和协议定价
所有图片(2)

About This Item

MDL號碼:
MFCD02097475
分類程式碼代碼:
12352203
NACRES:
NA.41

生物源

mouse

共軛

unconjugated

抗體表格

purified immunoglobulin

抗體產品種類

primary antibodies

無性繁殖

1F6, monoclonal

形狀

buffered aqueous solution

物種活性

human

技術

indirect ELISA: suitable
western blot: 1-5 μg/mL

同型

IgG1κ

GenBank登錄號

BC031056.1

UniProt登錄號

P15884

運輸包裝

dry ice

儲存溫度

−20°C

目標翻譯後修改

unmodified

基因資訊

human ... TCF4(6925)

一般說明

Transcription factor 4 (TCF4), also known as E2-2, is a helix-loop-helix transcription factor. It is part of the E protein family and is expressed in the cornea during development. The gene encoding TCF4 is localized on human chromosome 18q21.

免疫原

TCF4 (AAH31056.1, 1 a.a. ~ 365 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Sequence
MHHQQRMAALGTDKELSDLLDFSAMFSPPVSSGKNGPTSLASGHFTGSNVEDRSSSGSWGNGGHPSPSRNYGDGTPYDHTTSRDLGSHDNLSPPFVNSRIQSKTERGSYSSYGRESNLQGCHQQSLLGGDMDMGNPGTLSPTKPGSQYYQYSSNNPRRRPLHSSAMEVQTKKVRKVPPGLPSSVYAPSASTADYNRDSPGYPSSKPATSTFPSSFFMQDGHHSSDPWSSSSGMNQPGYAGMLGNSSHIPQSSSYCSLHPHERLSYPSHSSADINSSLPPMSTFHRSGTNHYSTSSCTPPANGTDSIMANRGSGAAGSSQTGDALGKALASIYSPDHTNNSFSSNPSTPVGSPPSLSAGTAVWSRN

生化／生理作用

Transcription factor 4 (TCF4) acts a regulator of cellular growth and differentiation. It has a role in the development of central nervous system. Defects in TCF4 gene are associated with Pitt-Hopkins syndrome. The protein has also been linked to susceptibility to schizophrenia.

外觀

Solution in phosphate buffered saline, pH 7.4

法律資訊

GenBank is a registered trademark of United States Department of Health and Human Services

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Not finding the right product?  

Try our 产品选型工具.

儲存類別代碼

10 - Combustible liquids

閃點（°F）

Not applicable

閃點（°C）

Not applicable

個人防護裝備

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

分析证书(COA)

输入产品批号来搜索 分析证书(COA) 。批号可以在产品标签上"批“ （Lot或Batch）字后找到。

已有该产品？

在文件库中查找您最近购买产品的文档。

访问文档库

TGC repeat expansion in the TCF4 gene increases the risk of Fuchs' endothelial corneal dystrophy in Australian cases.
Kuot A
PLoS ONE, 12(8), e0183719-e0183719 (2017)
TCF4 deletions in Pitt-Hopkins Syndrome.
Giurgea L
Human Mutation, 29(11), E242-E251 (2008)
TCF4 gene polymorphism is associated with cognition in patients with schizophrenia and healthy controls.
Journal of Psychiatric Research, 95-101 (2015)
Complex translocation disrupting TCF4 and altering TCF4 isoform expression segregates as mild autosomal dominant intellectual disability.
Maduro V
Orphanet Journal of Rare Diseases, 11(1), 62-62 (2016)
Association of TCF4 polymorphisms and Fuchs' endothelial dystrophy: a meta-analysis.
Li D
BMC Ophthalmology, 15, 61-61 (2015)

我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

联系技术服务部门