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Merck

U100

Sigma-Aldrich

乌拉地尔 盐酸盐

solid

别名:

6-[[3-[4-(o-甲氧苯基)-1-哌嗪基] 丙基] 氨基]-1,3-二甲基尿嘧啶 盐酸盐

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About This Item

经验公式(希尔记法):
C20H29N5O3 · HCl
CAS号:
分子量:
423.94
MDL號碼:
分類程式碼代碼:
12352200
PubChem物質ID:
NACRES:
NA.77

形狀

solid

顏色

white

溶解度

H2O: soluble 25 mg/mL, clear, colorless to very faintly yellow

SMILES 字串

Cl[H].COc1ccccc1N2CCN(CCCNC3=CC(=O)N(C)C(=O)N3C)CC2

InChI

1S/C20H29N5O3.ClH/c1-22-18(15-19(26)23(2)20(22)27)21-9-6-10-24-11-13-25(14-12-24)16-7-4-5-8-17(16)28-3;/h4-5,7-8,15,21H,6,9-14H2,1-3H3;1H

InChI 密鑰

KTMLZVUAXJERAT-UHFFFAOYSA-N

一般說明

肾上腺受体 α1a 基因 (ADRA1A) 定位于人类染色体 8p21.2,编码 α-肾上腺素能受体。

生化/生理作用

α1-肾上腺素受体拮抗剂;5-HT1A 5-羟色胺受体部分激动剂;抗高血压。
肾上腺素受体 α1a 基因 (ADRA1A) 参与平滑肌收缩。全身血管如皮肤、胃肠系统、泌尿生殖系统、肾和脑的血管收缩也需要它。ADRA1A 在肝脏脂肪组织糖原分解和糖异生中起主要作用。对交感神经系统也起关键作用。

準備報告

盐酸乌拉地尔溶于水,浓度为 25 mg/mL,得到澄清、无色至非常淡黄色溶液。

象形圖

Exclamation mark

訊號詞

Warning

危險聲明

危險分類

Acute Tox. 4 Oral

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

dust mask type N95 (US), Eyeshields, Gloves


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