推荐产品
形狀
solid
顏色
white
溶解度
H2O: soluble 25 mg/mL, clear, colorless to very faintly yellow
SMILES 字串
Cl[H].COc1ccccc1N2CCN(CCCNC3=CC(=O)N(C)C(=O)N3C)CC2
InChI
1S/C20H29N5O3.ClH/c1-22-18(15-19(26)23(2)20(22)27)21-9-6-10-24-11-13-25(14-12-24)16-7-4-5-8-17(16)28-3;/h4-5,7-8,15,21H,6,9-14H2,1-3H3;1H
InChI 密鑰
KTMLZVUAXJERAT-UHFFFAOYSA-N
基因資訊
human ... ADRA1A(148) , ADRA1B(147) , ADRA1D(146) , HTR1A(3350)
一般說明
肾上腺受体 α1a 基因 (ADRA1A) 定位于人类染色体 8p21.2,编码 α-肾上腺素能受体。
生化/生理作用
α1-肾上腺素受体拮抗剂;5-HT1A 5-羟色胺受体部分激动剂;抗高血压。
肾上腺素受体 α1a 基因 (ADRA1A) 参与平滑肌收缩。全身血管如皮肤、胃肠系统、泌尿生殖系统、肾和脑的血管收缩也需要它。ADRA1A 在肝脏脂肪组织糖原分解和糖异生中起主要作用。对交感神经系统也起关键作用。
肾上腺素受体 α1a 基因 (ADRA1A) 参与平滑肌收缩。全身血管如皮肤、胃肠系统、泌尿生殖系统、肾和脑的血管收缩也需要它。ADRA1A 在肝脏脂肪组织糖原分解和糖异生中起主要作用。对交感神经系统也起关键作用。
準備報告
盐酸乌拉地尔溶于水,浓度为 25 mg/mL,得到澄清、无色至非常淡黄色溶液。
訊號詞
Warning
危險聲明
危險分類
Acute Tox. 4 Oral
儲存類別代碼
11 - Combustible Solids
水污染物質分類(WGK)
WGK 3
閃點(°F)
Not applicable
閃點(°C)
Not applicable
個人防護裝備
dust mask type N95 (US), Eyeshields, Gloves
MiR-19b and miR-16 cooperatively signaling target the regulator ADRA1A in Hypertensive heart disease
Biomedicine and Pharmacotherapy, 91(1), 1178-1183 (2017)
Malaria journal, 18(1), 146-146 (2019-04-25)
Plasmodium falciparum parasite is the most deadly species of human malaria, and the development of an effective vaccine that prevents P. falciparum infection and transmission is a key target for malarial elimination and eradication programmes. P. falciparum cell-traversal protein for
Infection and immunity, 87(6) (2019-04-03)
Plasmodium falciparum cell-traversal protein for ookinetes and sporozoites (PfCelTOS) is an advanced vaccine candidate that has a crucial role in the traversal of the malaria parasite in both mosquito and mammalian hosts. As recombinant purified proteins are normally poor immunogens
Journal of hypertension. Supplement : official journal of the International Society of Hypertension, 6(2), S65-S68 (1988-12-01)
The alpha-adrenoceptor antagonist urapidil influences central cardiovascular regulation, and this effect is unrelated to alpha-adrenoceptors. Since urapidil has appreciable affinity and selectivity for serotonin-1A (5HT1A) receptors, the activity of urapidil at these sites may be relevant for the centrally mediated
A targeted genome association study examining transient receptor potential ion channels, acetylcholine receptors, and adrenergic receptors in chronic fatigue syndrome/myalgic encephalomyelitis
BMC Medical Genetics, 17(1), 79-79 (2016)
我们的科学家团队拥有各种研究领域经验,包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系技术服务部门