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Merck
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Key Documents

SRP6430

Sigma-Aldrich

VEGF164 from mouse

recombinant, expressed in HEK 293 cells, ≥95% (SDS-PAGE)

别名:

VEGFA, VPF

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About This Item

分類程式碼代碼:
12352202
NACRES:
NA.32

生物源

mouse

重組細胞

expressed in HEK 293 cells

化驗

≥95% (SDS-PAGE)

形狀

lyophilized

分子量

calculated mol wt 19.3 kDa (no tag)
observed mol wt 23-25 kDa (DTT-reduced. Protein migrates due to glycosylation. Ala 27 is the predicted N-terminal.)

包裝

pkg of 10 μg

UniProt登錄號

運輸包裝

wet ice

儲存溫度

−20°C

基因資訊

mouse ... VEGFA(22339)

一般說明

Vascular endothelial growth factor A (VEGFA) is also known as Vascular permeability factor (VPF). VEGFA belongs to the PDGF/VEGF growth factor family. VEGFA is a glycosylated mitogen that specifically acts on endothelial cells and has various effects, including mediating increased vascular permeability, inducing angiogenesis, vasculogenesis and endothelial cell growth, promoting cell migration, and inhibiting apoptosis. Alternatively spliced transcript variants, encoding either freely secreted or cell-associated isoforms, have been characterized. VEGFA is produced by a group of three major isoforms as a result of alternative splicing and if any three isoforms are produced (VEGFA120, VEGFA164, and VEGFA188) then this will not result in vessel defects and death of the full VEGFA knockout in mice.

外觀

Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally Mannitol or Trehalose is added as protectants before lyophilization.

重構

Centrifuge the vial prior to opening. Reconstitute in sterile PBS, pH 7.4 to a concentration of 50 μg/mL. Do not vortex. This solution can be stored at 2-8°C for up to 1 month. For extended storage, it is recommended to store at -20°C.

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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