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生物源
mouse
重組細胞
expressed in E. coli
化驗
≥98% (HPLC)
≥98% (SDS-PAGE)
形狀
lyophilized
分子量
9.2 kDa
包裝
pkg of 25 μg
技術
cell culture | mammalian: suitable
雜質
<0.1 EU/μg endotoxin, tested
顏色
white
UniProt登錄號
運輸包裝
wet ice
儲存溫度
−20°C
基因資訊
mouse ... RETNIG(245195)
一般說明
RELMγ belongs to a unique family of tissue-specific cytokines termed FIZZ (found in inflammatory zone) and RELM. The other three known members of this family; Resistin, RELMα, and RELMβ, are 85-94 amino acid secreted proteins sharing a conserved C-terminal domain characterized by 10 cysteine residues with a unique spacing motif of C-X11-C-X8-C-X-C-X3-C-X10-C-X-C-X-C-X9-C-C. RELMγ is most closely related to RELMα, but is distinctly secreted to bone marrow, spleen, lung, and in peripheral blood granulocytes. The physiological role of RELMγ may include the promotion or regulation of promyelocytic differentiation, although the specific molecular targets of RELMγ have not been identified. Recombinant murine RELMγ is a 9.2 kDa monomeric protein containing 88 amino acid residues.
生化／生理作用
RELMγ belongs to a unique family of tissue-specific cytokines termed FIZZ (found in inflammatory zone) and RELM. Recombinant murine RELMg is a 9.2 kDa monomeric protein containing 88 amino acid residues.
序列
EGTLESIVEK KVKELLANRD DCPSTVTKTF SCTSITASGR LASCPSGMTV TGCACGYGCG SWDIRDGNTC HCQCSTMDWA TARCCQLA
外觀
Lyophilized with no additives.
重構
Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/ml. Do not vortex. This solution can be stored at 2-8°C for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20°C to -80°C.
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
B Gerstmayer et al.
Genomics, 81(6), 588-595 (2003-06-05)
We have identified RELMgamma, a novel member of the resistin-like molecule/found in inflammatory zone (RELM/FIZZ) family in mice and rats. Microarray and real-time RT-PCR experiments revealed a repression of RELMgamma mRNA in nasal respiratory epithelium of cigarette smoke-exposed versus untreated
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