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生物源
human
重組細胞
expressed in baculovirus infected Sf9 cells
化驗
≥49% (SDS-PAGE)
形狀
aqueous solution
分子量
114 kDa
包裝
pkg of 20 μg
UniProt登錄號
運輸包裝
dry ice
儲存溫度
−70°C
基因資訊
human ... EZH2(2146)
一般說明
Human EZH2 (GenBank Accession No. NM_004456), amino acids 2-end with N-terminal His-GST-tag, MW= 114 kDa, expressed in a Sf9 Baculovirus expression system.
外觀
Formulated in 40 mM Tris-HCl, pH 8.0, 110 mM NaCl, 2.2 mM KCl, 16 mM glutathione, 20% glycerol and 3 mM DTT.
儲存類別代碼
10 - Combustible liquids
水污染物質分類（WGK）
WGK 1
閃點（°F）
Not applicable
閃點（°C）
Not applicable
Zheng Zhang et al.
Nucleic acids research, 45(16), 9348-9360 (2017-06-24)
In eukaryotic cells, the gene expression status is strictly controlled by epigenetic modifications on chromatin. The repressive status of chromatin largely contributes to HIV latency. Studies have shown that modification of histone H3K27 acts as a key molecular switch for
Rakotobe, D. et al.
Journal of Virology, 5, 32-32 (2008)
Sooryanarayana Varambally et al.
Science (New York, N.Y.), 322(5908), 1695-1699 (2008-11-15)
Enhancer of zeste homolog 2 (EZH2) is a mammalian histone methyltransferase that contributes to the epigenetic silencing of target genes and regulates the survival and metastasis of cancer cells. EZH2 is overexpressed in aggressive solid tumors by mechanisms that remain
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