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Merck
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Key Documents

SRP0336

Sigma-Aldrich

SYK Catalytic Subunit active human

recombinant, expressed in baculovirus infected Sf9 cells, ≥60% (SDS-PAGE)

别名:

p72-Syk, spleen tyrosine kinase

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About This Item

分類程式碼代碼:
12352204
NACRES:
NA.32

生物源

human

重組細胞

expressed in baculovirus infected Sf9 cells

化驗

≥60% (SDS-PAGE)

形狀

aqueous solution

比活性

≥139 pmol/min-μg

分子量

58 kDa

包裝

pkg of 10 μg

技術

activity assay: suitable
inhibition assay: suitable

NCBI登錄號

UniProt登錄號

運輸包裝

dry ice

儲存溫度

−70°C

基因資訊

human ... SYK(6850)

一般說明

Recombinant human SYK, (Genbank Accession No. NM_003177), amino acids 359-635 (end) with an N-terminal GST-tag, MW = 58 kDa, expressed in Sf9 insect cells.

應用

Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.

外觀

Fomulated in 40 mM Tris-HCl, pH 8, 110 mM NaCl, 2.2 mM KCl, 3 mM DTT, 4 mM glutathione, and 20% glycerol.

儲存類別代碼

12 - Non Combustible Liquids

水污染物質分類(WGK)

WGK 1

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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Tomoko Takano et al.
Antioxidants & redox signaling, 4(3), 533-541 (2002-09-07)
Oxidative stress induces the activation of multiple signaling pathways related to various cellular responses. In B cells, Syk has a crucial role in intracellular signal transduction induced by oxidative stress as well as antigen receptor engagement. Treatment of B cells
Christopher S Navara
Current pharmaceutical design, 10(15), 1739-1744 (2004-06-08)
The spleen tyrosine kinase Syk is an enigmatic protein tyrosine kinase functional in a number of diverse cellular processes. It is best known as a non receptor protein tyrosine kinase involved in signal transduction in cells of hematopoietic origin and

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