SML4058

Florfenicol

≥98% (HPLC)

• 别名: (-)-Florfenicol, 2,2-Dichloro-N-((1R,2S)-3-fluoro-1-hydroxy-1-(4-(methylsulfonyl)phenyl)propan-2-yl)acetamide, 2,2-Dichloro-N-[(1S,2R)-1-(fluoromethyl)-2-hydroxy-2-[4-(methylsulfonyl)phenyl]ethyl]acetamide, SCH 25298
• 经验公式（希尔记法）: C₁₂H₁₄Cl₂FNO₄S
• CAS号: 73231-34-2
• 分子量: 358.21
• MDL號碼: MFCD20926274
• 分類程式碼代碼: 12352200

属性

• 品質等級: 100
• 化驗: ≥98% (HPLC)
• 形狀: powder
• 顏色: white to beige
• 溶解度: DMSO: 2 mg/mL, clear
• 儲存溫度: -10 to -25°C
• SMILES 字串: ClC(C(N[C@@H]([C@H](O)C1=CC=C(S(C)(=O)=O)C=C1)CF)=O)Cl
• InChI: 1S/C12H14Cl2FNO4S/c1-21(19,20)8-4-2-7(3-5-8)10(17)9(6-15)16-12(18)11(13)14/h2-5,9-11,17H,6H2,1H3,(H,16,18)/t9-,10-/m1/s1
• InChI 密鑰: AYIRNRDRBQJXIF-NXEZZACHSA-N

说明

生化／生理作用

Broad-spectrum antibiotic that inhibits protein synthesis by binding to the 50S ribosomal subunit of bacteria.



Florfenicol is a broad-spectrum antibiotic that is primarily used in veterinary medicine to treat respiratory infections in cattle and swine, and to prevent Salmonella infection in poultry. It has favorable ADME properties and is a fluorinated analog of chloramphenicol that has good tissue penetration and is resistant to chloramphenicol acetyltransferase inactivation. Florfenicol inhibits ribosomal activity and effectively inhibits bacterial protein synthesis, which makes it effective against various bacteria. However, oral administration of florfenicol may alter animal microbiota.

安全信息

• 象形圖: GHS08,GHS09
• 訊號詞: Danger
• 危險聲明: H361fd,H372,H410
• 防範說明: P202 - P260 - P264 - P273 - P280 - P308 + P313
• 危險分類: Aquatic Acute 1 - Aquatic Chronic 1 - Repr. 2 - STOT RE 1
• 標靶器官: Liver,Brain,Testes,Spinal cord,Blood,gallbladder
• 儲存類別代碼: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable