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Merck

SML3612

Sigma-Aldrich

Ganoderic acid D

≥95% (HPLC)

别名:

(7β)-7-Hydroxy-3,11,15,23-tetraoxolanost-8-en-26-oic acid, GAD

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About This Item

经验公式(希尔记法):
C30H42O7
分子量:
514.65
MDL號碼:
分類程式碼代碼:
12352106
分類程式碼代碼:
12352200
NACRES:
NA.21

品質等級

化驗

≥95% (HPLC)

形狀

powder

顏色

white to beige

溶解度

DMSO: 2 mg/mL, clear

儲存溫度

-10 to -25°C

生化/生理作用

Ganoderic acid D is one of major triterpenes isolated from Ganoderma lucidum that exhibit potent anticancer properties. Ganoderic acid D inhibits the energy reprogramming of colon cancer cells including glucose uptake, lactate, and pyruvate and acetyl-coenzyme production through SIRT3 upregulation via acetylated cyclophilin D inhibition.

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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Zhendong Liu et al.
European journal of pharmacology, 824, 72-77 (2018-01-29)
Ganoderic acid D (GAD) is a highly oxygenated tetracyclic triterpenoid. This study aims to assess the effects of GAD on the energy metabolism of colon cancer through the regulation of SIRT3 expression and whether this effect is related to acetylated

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