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品質等級
化驗
≥98% (HPLC)
形狀
powder
顏色
white to beige
溶解度
DMSO: 2 mg/mL, clear
儲存溫度
2-8°C
SMILES 字串
FC1=CC2=C(C=C1)SC(S(NC3=CC=C(C=C3S(C)(=O)=O)C4=NC(C(O)=O)=CS4)(=O)=O)=C2C
生化／生理作用
TY-51469 is a potent and selective chymase inhibitor that prevents development and progression of non-alcoholic steatohepatitis in rats. TY-51469 inhibits activation of intestinal MMP-9 and prevents intestinal damage in indomethacin-induced small intestinal damage in rats. Also TY-51469 might protect against pancreatic islet disorganization.
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
Significance of chymase-dependent matrix metalloproteinase-9 activation on indomethacin-induced small intestinal damages in rats
Kakimoto K, Takai S, Murano M, Ishida K, Yoda Y, Inoue T, Jin D, Umegaki E, Higuchi K
Journal of Pharmacology and Experimental Therapeutics, 332, 684-689 (2010)
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