SML3450

PA-8

≥95% (HPLC)

• 别名: 2-​Amino-​5,​8-​dihydro-​5-​[3-​methoxy-​4-​(2-​propen-​1-​yloxy)​phenyl]​-pyrido[2,​3-​d]​pyrimidine-​4,​7(3H,​6H)​-​dione, PA 8
• 经验公式（希尔记法）: C₁₇H₁₈N₄O₄
• CAS号: 878437-15-1
• 分子量: 342.35
• MDL號碼: MFCD07400226
• 分類程式碼代碼: 12352200
• NACRES: NA.77

属性

• 品質等級: 100
• 化驗: ≥95% (HPLC)
• 形狀: powder
• 顏色: white to beige
• 溶解度: DMSO: 2 mg/mL, clear
• 儲存溫度: -10 to -25°C

说明

生化／生理作用

PA-8 is a potent and selective PACAP type I (PAC1) receptor agonist that inhibits the phosphorylation of CREB induced by PACAP in PAC1- receptor-expressing CHO cells. PA-8 blocks PACAP-induced aversive responses and mechanical allodynia in mice.

安全信息

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable