SML3336

VU0155056

≥98% (HPLC)

• 别名: 5W0, ML272, N-(2-{4-[2-Oxo-2,3-dihydro-1H-benzo(d)imidazol-1-yl]piperidin-1-yl}ethyl)-2-naphthamide, N-[2-[4-(2,3-Dihydro-2-oxo-1H-benzimidazol-1-yl)-1-piperidinyl]ethyl]-2-naphthalenecarboxamide, VU 0155056
• 经验公式（希尔记法）: C₂₅H₂₆N₄O₂
• CAS号: 1130067-18-3
• 分子量: 414.50
• MDL號碼: MFCD22416857
• 分類程式碼代碼: 12352200
• NACRES: NA.77

属性

• 品質等級: 100
• 化驗: ≥98% (HPLC)
• 形狀: powder
• 儲存條件: desiccated
• 顏色: white to beige
• 溶解度: DMSO: 2 mg/mL, clear
• 儲存溫度: -10 to -25°C

说明

生化／生理作用

VU0155056 is a catalytic site-targeting phospholipase D inhibitor (PLD1/PLD2 IC50 = 81 nM/240 nM by cell-free enzymatic assays; substrate = di-palmitoyl-PLC) that effectively suppresses the cellular PLD activity in GFP-PLD2-overexpressing HEK293 cells as well as PMA-stimulated non-small-cell lung cancer (NSCLC) Calu-1 cells with predominant PLD1 activity (IC50 = 380 nM and 21 nM, respectively).

安全信息

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: No data available
• 閃點（°C）: No data available