SML3136

CGP-54626

≥95% (HPLC)

• 别名: CGP-54626A, Cyclohexylmethyl((S)-3-((S)-1-(3,4-dichlorophenyl)ethylamino)-2-hydroxypropyl)phosphinic acid hydrochloride, P-(Cyclohexylmethyl)-P -[(2S )-3-[[(1S )-1-(3,4-dichlorophenyl)ethyl]amino]-2-hydroxypropyl]-phosphinic acid hydrochloride, [3-[N-[(1S)-1-(3,4-Dichlorophenyl)ethyl]amino]-(2S)-hydroxypropyl](cyclohexylmethyl)phosphinic acid hydrochloride, [S-(R*,R*)]-[3-[[1-(3,4-Dichlorophenyl)ethyl]amino]-2-hydroxypropyl](cyclohexylmethyl) phosphinic acid hydrochloride
• 经验公式（希尔记法）: C₁₈H₂₈Cl₂NO₃P · HCl
• CAS号: 149184-21-4
• 分子量: 444.76
• MDL號碼: MFCD09878291
• 分類程式碼代碼: 12352200
• NACRES: NA.77

属性

• 品質等級: 100
• 化驗: ≥95% (HPLC)
• 形狀: powder
• 顏色: white to beige
• 儲存溫度: −20°C
• SMILES 字串: ClC1=C(C=CC([C@@H](NC[C@@H](CP(CC2CCCCC2)(O)=O)O)C)=C1)Cl.Cl
• InChI: 1S/C18H28Cl2NO3P.ClH/c1-13(15-7-8-17(19)18(20)9-15)21-10-16(22)12-25(23,24)11-14-5-3-2-4-6-14;/h7-9,13-14,16,21-22H,2-6,10-12H2,1H3,(H,23,24);1H/t13-,16-;/m0./s1
• InChI 密鑰: ZQCFHOVIXCJPLE-LINSIKMZSA-N

说明

生化／生理作用

CGP-54626 is an orally available, potent selective GABAB receptor antagonist with an IC50 of 4 nM that binds to orthosteric site of (Kd = 33.1 nM) GABA(B)-R1. CGP 54626 decreases a sensitivity to ethanol in Drosophila melanogaster model.

安全信息

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable