跳转至内容
Merck
所有图片(1)

主要文件

查看所有文档

SML2127

Sigma-Aldrich

地那唑

≥98% (HPLC)

别名:

2- [1-（4-氯苯基）-环丙基] -7-碘-5-氧代-4,5-二氢吡唑并[1,5-a]喹唑啉-3-碳酸酯

登录查看公司和协议定价
所有图片(1)

About This Item

经验公式（希尔记法）:
C20H12ClIN4O
CAS号:
2226517-75-3
分子量:
486.69
分類程式碼代碼:
12352200
NACRES:
NA.77

化驗

≥98% (HPLC)

形狀

powder

顏色

white to beige

溶解度

DMSO: 2 mg/mL, clear (warmed)

儲存溫度

2-8°C

SMILES 字串

IC1=CC=C(N2C(NC3=O)=C(C#N)C(C4(CC4)C5=CC=C(Cl)C=C5)=N2)C3=C1

InChI

1S/C20H12ClIN4O/c21-12-3-1-11(2-4-12)20(7-8-20)17-15(10-23)18-24-19(27)14-9-13(22)5-6-16(14)26(18)25-17/h1-6,9H,7-8H2,(H,24,27)

InChI 密鑰

VABPBCMFKJDOHP-UHFFFAOYSA-N

生化／生理作用

Dynapyrazole-A是一种有效的动力蛋白抑制剂。Dynapyrazole-A可抑制微管活性，而不抑制基础ATPase活性。
动力蛋白抑制剂

儲存類別代碼

11 - Combustible Solids

水污染物質分類（WGK）

WGK 3

閃點（°F）

Not applicable

閃點（°C）

Not applicable

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

It looks like we've run into a problem, but you can still download Certificates of Analysis from our 文件 section.

如需帮助，请联系 客户支持

已有该产品？

在文件库中查找您最近购买产品的文档。

访问文档库

Jonathan B Steinman et al.
eLife, 6 (2017-05-20)
Cytoplasmic dyneins are motor proteins in the AAA+ superfamily that transport cellular cargos toward microtubule minus-ends. Recently, ciliobrevins were reported as selective cell-permeable inhibitors of cytoplasmic dyneins. As is often true for first-in-class inhibitors, the use of ciliobrevins has in
Alexander S Zhovmer et al.
ACS nano, 15(11), 17528-17548 (2021-10-23)
Microtubules (MTs) and MT motor proteins form active 3D networks made of unstretchable cables with rod-like bending mechanics that provide cells with a dynamically changing structural scaffold. In this study, we report an antagonistic mechanical balance within the dynein-kinesin microtubular

我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

联系技术服务部门