跳转至内容
Merck
所有图片(1)

主要文件

查看所有文档

SML2054

Sigma-Aldrich

SEA0400

≥98% (HPLC)

别名:

2-[4-[(2,5-二氟苯基)甲氧基]苯氧基]-5-乙氧基苯胺, 2- [4-[（2,5-二氟苯基）甲氧基]苯氧基] -5-乙氧苯胺

登录查看公司和协议定价
所有图片(1)

About This Item

经验公式（希尔记法）:
C21H19F2NO3
CAS号:
223104-29-8
分子量:
371.38
MDL號碼:
MFCD07772188
分類程式碼代碼:
12352200
NACRES:
NA.77

化驗

≥98% (HPLC)

形狀

powder

顏色

white to beige

運輸包裝

ambient

儲存溫度

−20°C

SMILES 字串

CCOC1=CC=C(OC2=CC=C(OCC3=C(F)C=CC(F)=C3)C=C2)C(N)=C1

InChI

1S/C21H19F2NO3/c1-2-25-18-8-10-21(20(24)12-18)27-17-6-4-16(5-7-17)26-13-14-11-15(22)3-9-19(14)23/h3-12H,2,13,24H2,1H3

InChI 密鑰

YSUBLPUJDOWYDP-UHFFFAOYSA-N

生化／生理作用

Na+−Ca++ 交换蛋白（NCX）的有效选择性抑制剂。
SEA0400是Na+/Ca2+交换蛋白（NCX）的有效选择性抑制剂。SEA0400可有效抑制大鼠星形胶质细胞、小胶质细胞、培养神经元和心肌细胞中Na+/Ca2+交换蛋白的活性。

儲存類別代碼

11 - Combustible Solids

水污染物質分類（WGK）

WGK 3

閃點（°F）

Not applicable

閃點（°C）

Not applicable

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

It looks like we've run into a problem, but you can still download Certificates of Analysis from our 文件 section.

如需帮助，请联系 客户支持

已有该产品？

在文件库中查找您最近购买产品的文档。

访问文档库

其他客户在看

Slide 1 of 2

1 of 2

雷诺嗪 二盐酸盐 ≥98% (HPLC), powder

Sigma-Aldrich

R6152

雷诺嗪 二盐酸盐

毒胡萝卜素 ≥98% (HPLC), solid film

Sigma-Aldrich

T9033

毒胡萝卜素

Torsten Christ et al.
European journal of pharmacology, 788, 286-293 (2016-07-05)
The Na(+)/Ca(2+) exchanger (NCX) plays a major role in myocardial Ca(2+) homoeostasis, but is also considered to contribute to the electrical instability and contractile dysfunction in chronic atrial fibrillation (AF). Here we have investigated the effects of the selective NCX
Kanna Yamashita et al.
Naunyn-Schmiedeberg's archives of pharmacology, 389(11), 1205-1214 (2016-08-03)
Recently, YM-244769 (N-(3-aminobenzyl)-6-{4-[(3-fluorobenzyl)oxy]phenoxy} nicotinamide) has been reported as a new potent and selective Na
T Matsuda et al.
The Journal of pharmacology and experimental therapeutics, 298(1), 249-256 (2001-06-16)
The effect of the newly synthesized compound 2-[4-[(2,5-difluorophenyl)methoxy]phenoxy]-5-ethoxyaniline (SEA0400) on the Na+-Ca2+ exchanger (NCX) was investigated and compared against that of 2-[2-[4-(4-nitrobenzyloxy)phenyl]ethyl]isothiourea (KB-R7943). In addition, the effects of SEA0400 on reperfusion injury in vitro and in vivo were examined. SEA0400

我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

联系技术服务部门