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Merck

SML1787

Sigma-Aldrich

仙草素

≥98% (HPLC), powder, anti-inflammatory agent

别名:

2-(3,4-二甲氧基苯基)-5,6,7-三甲氧基铬-4-酮, 2-(3,4-二羟基苯基)-5,6,7-三羟基-4 H -1-苯并吡喃-4-酮, 3,5,6,7-五甲氧基黄酮, 6-羟基木犀草素 5,6,7,3′,4′-五甲基醚, 甜橙黄酮

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About This Item

经验公式(希尔记法):
C20H20O7
CAS号:
分子量:
372.37
Beilstein:
345748
分類程式碼代碼:
12352200
NACRES:
NA.77

product name

仙草素, ≥98% (HPLC)

品質等級

化驗

≥98% (HPLC)

形狀

powder

顏色

white to beige

溶解度

DMSO: 3 mg/mL, clear (warmed)

儲存溫度

2-8°C

SMILES 字串

O=C1C=C(C2=CC(OC)=C(OC)C=C2)OC3=C1C(OC)=C(OC)C(OC)=C3

InChI

1S/C20H20O7/c1-22-13-7-6-11(8-15(13)23-2)14-9-12(21)18-16(27-14)10-17(24-3)19(25-4)20(18)26-5/h6-10H,1-5H3

InChI 密鑰

LKMNXYDUQXAUCZ-UHFFFAOYSA-N

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一般說明

甜橙黄酮是一种植物来源的多甲氧基黄酮。主要分布于肾茶(原变种)Orthosiphon aristatus var. aristatus和各种柑橘类水果中。相比其他部位,甜橙黄酮在柑橘类水果的皮中大量存在。

應用

甜橙黄酮可作为柑橘类黄酮,研究其在棕榈酸(PA)处理HepG2细胞中通过激活AMP活化蛋白激酶(AMPK)而发挥抗成脂作用。还可作为标准品,通过超高效液相色谱法定量分析猫须草Orthosiphon stamineus提取物中的多酚含量。

生化/生理作用

甜橙黄酮是一种具有抗炎和抗增殖活性的柑桔类黄酮。它还显示出可增强脂肪生成和脂解作用。具有抗癌、抗微生物、抗痴呆、抗氧化、抗肥胖、抗锥虫和血管舒张活性。可抑制P-糖蛋白(P-gp)、外排转运蛋白和乳腺癌耐药蛋白(BCRP)。甜橙黄酮可作为黄酮类化学增敏剂。

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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