SML1370

A-779 trifluoroacetate salt

≥98% (HPLC)

• 别名: A779 trifluoroacetate salt, Asp1-Arg2-Val3-Tyr4-Ile5-His6-D-Ala7, D-Ala7-Ang-(1-7), DRVYIHA (Modification: Ala-7 = D-Ala), DRVYIHa trifluoroacetate salt, H-Asp-Arg-Val-Tyr-Ile-His-D-Ala-OH trifluoroacetate salt, [7-D-ALA]-angiotensin-(1-7) trifluoroacetate salt
• 经验公式（希尔记法）: C₃₉H₆₀N₁₂O₁₁ · xC₂HF₃O₂
• CAS号: 159432-28-7
• 分子量: 872.97 (free base basis)
• 分類程式碼代碼: 12352200
• NACRES: NA.77

属性

• 品質等級: 100
• 化驗: ≥98% (HPLC)
• 形狀: lyophilized powder
• 顏色: white to off-white
• 運輸包裝: wet ice
• 儲存溫度: −20°C

说明

生化／生理作用

A-779 (D-Ala7-Ang-(1-7)) is a potent and selective antagonist of angiotensin (1-7), an endogenous peptide that acts through activation of a non-AT1, non-AT2 receptor, Mas, and opposes the activity of angiotensin. A-779 has an IC₅₀ of 0.3 nM for Mas with negligible affinity for either AT1R or AT2R.

This blocking angiotensin action affects cardiovascular function.

安全信息

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable