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品質等級
化驗
≥95% (HPLC)
形狀
powder
儲存條件
desiccated
顏色
white to light brown
溶解度
DMSO: 5 mg/mL, clear (warmed)
儲存溫度
−20°C
InChI
1S/C9H13NO3/c1-5(10)9(13)6-2-3-7(11)8(12)4-6/h2-5,9,11-13H,10H2,1H3/t5-,9-/m0/s1
InChI 密鑰
GEFQWZLICWMTKF-CDUCUWFYSA-N
生化／生理作用
α-Methylnorepinephrine (αMNE) is an α2-adrenergic agonist and is useful in cardiopulmonary resuscitation (CPR) during myocardial dysfunction especially in animals. αMNE improves water absorption in the jejunum and is blood-brain barrier impermeable.
α-Methylnorepinephrine is a sympathomimetic amine and vasoconstrictor. α-Methylnorepinephrine is used clinically in dentistry in local anesthetic solutions.
特點和優勢
This compound is featured on the α2-Adrenoceptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
訊號詞
Warning
危險分類
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
標靶器官
Respiratory system
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
alpha-Methylnorepinephrine, a selective alpha2-adrenergic agonist for cardiac resuscitation
Sun S, et al.
Journal of the American College of Cardiology, 37(3), 951-956 (2001)
Effect of alpha-methylnorepinephrine, an alpha 2-adrenergic agonist, on jejunal absorption in neurally intact conscious dog
Herkes SM, et al.
Digestive Diseases and Sciences, 38(9), 1645-1650 (1993)
商品
Review alpha 2 adrenoceptors as well as their agonists, antagonists, and tissue expression patterns. We suggest several modulators and alternatives for working with a-2 adrenoreceptors.
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