SML0476

Rabeprazole sodium

≥98% (HPLC)

• 别名: 2-([4-(3-Methoxypropoxy)-3-methylpyridin-2-yl]methylsulfinyl)-1H-benzo[d]imidazole, Pariprazole
• 经验公式（希尔记法）: C₁₈H₂₀N₃O₃S · Na
• CAS号: 117976-90-6
• 分子量: 381.42
• 分類程式碼代碼: 12352200
• PubChem物質ID: 329825431
• NACRES: NA.77

属性

• 化驗: ≥98% (HPLC)
• 形狀: powder
• 儲存條件: desiccated
• 顏色: white to beige
• 溶解度: H₂O: 10 mg/mL (clear solution)
• 運輸包裝: wet ice
• 儲存溫度: −20°C
• SMILES 字串: [Na+].COCCCOc1ccnc(CS(=O)c2nc3ccccc3[n-]2)c1C
• InChI: 1S/C18H20N3O3S.Na/c1-13-16(19-9-8-17(13)24-11-5-10-23-2)12-25(22)18-20-14-6-3-4-7-15(14)21-18;/h3-4,6-9H,5,10-12H2,1-2H3;/q-1;+1
• InChI 密鑰: KRCQSTCYZUOBHN-UHFFFAOYSA-N
• 基因資訊: human ... ATP4A(495) , ATP4B(496)

说明

應用

Rabeprazole sodium has been used as a proton pump inhibitor (PPI) to study its effects on spontaneous uterine contractile activity in pregnant women.

生化／生理作用

Rabeprazole sodium is gastric proton pump inhibitor. It suppresses the production of acid in the stomach by inhibiting the gastric H+/K+ATPase (hydrogen-potassium adenosine triphosphatase) at the secretory surface of the gastric parietal cell. Rabeprazole sodium has been used clinically to treat acid-reflux disorders (GERD), peptic ulcer disease, H. pylori eradication, and prevent gastroinetestinal bleeds associated with NSAID use.

安全信息

• 象形圖: GHS07
• 訊號詞: Warning
• 危險聲明: H302,H413
• 防範說明: P264 - P270 - P273 - P301 + P312 - P501
• 危險分類: Acute Tox. 4 Oral - Aquatic Chronic 4
• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable