SML0340
Hydroxy-Dynasore
≥98% (HPLC)
别名:
3-Hydroxy-2-naphthalenecarboxylic acid 2-[(2,4,5-trihydroxyphenyl)methylene]hydrazide, 3-Hydroxy-N′-[(2,4,5-trihydroxyphenyl)methylidene]naphthalene-2-carbohydrazide
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所有图片(1)
About This Item
经验公式（希尔记法）:
C18H14N2O5
CAS号:
分子量:
338.31
MDL號碼:
分類程式碼代碼:
12352200
PubChem物質ID:
NACRES:
NA.77
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品質等級
化驗
≥98% (HPLC)
形狀
powder
儲存條件
protect from light
顏色
faintly yellow to dark yellow
溶解度
DMSO: >10 mg/mL
儲存溫度
2-8°C
SMILES 字串
Oc1cc(O)c(\C=N\NC(=O)c2cc3ccccc3cc2O)cc1O
InChI
1S/C18H14N2O5/c21-14-8-17(24)16(23)7-12(14)9-19-20-18(25)13-5-10-3-1-2-4-11(10)6-15(13)22/h1-9,21-24H,(H,20,25)/b19-9+
InChI 密鑰
UAXHPUSKEWEOAP-DJKKODMXSA-N
生化／生理作用
Hydroxy-Dynasore is a cell permeable and potent dynamin inhibitor that prevents uptake of recombinant botulinum neurotoxin A heavy chain binding domain (BoNT/A-Hc). Apparently, Hydroxy-Dynasore prevents dynamin-mediated fission of endocytic vesicles from the plasma membrane.
其他說明
Air sensitive.
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
其他客户在看
Thao Nguyen et al.
Oncogene, 38(35), 6283-6300 (2019-07-18)
N-cadherin adhesion has been reported to enhance cancer and neuronal cell migration either by mediating actomyosin-based force transduction or initiating fibroblast growth factor receptor (FGFR)-dependent biochemical signalling. Here we show that FGFR1 reduces N-cadherin-mediated cell migration. Both proteins are co-stabilised
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