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品質等級
化驗
≥98% (HPLC)
形狀
powder
顏色
white to tan
溶解度
DMSO: ≥5 mg/mL at ~60 °C
儲存溫度
2-8°C
SMILES 字串
OC(=O)COc1ccc(cc1)\C=C2/SC(=O)NC2=O
InChI
1S/C12H9NO5S/c14-10(15)6-18-8-3-1-7(2-4-8)5-9-11(16)13-12(17)19-9/h1-5H,6H2,(H,14,15)(H,13,16,17)/b9-5-
InChI 密鑰
WXMCOLGPDOYHNK-UITAMQMPSA-N
應用
GPR35 Agonist, Compound 10, may be used in GPR35-mediated cell signaling studies.
生化／生理作用
GPR35 agonist Compound 10 is a GPR35 agonist the binds with higher affinity than other known agonists, such as kynurenic acid and zaprinast. Compound 10 was more potent than zaniprast (pEC50 = 5.3 vs 4.18) for recombinantly expressed human GPR35, and unlike zaprinast, is equipotent for human and rat GPR35
訊號詞
Warning
危險聲明
危險分類
Eye Irrit. 2
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
Ida Marie Modvig et al.
American journal of physiology. Endocrinology and metabolism, 320(5), E874-E885 (2021-03-02)
The aim of this study was to explore individual amino acid-stimulated GLP-1 responses and the underlying stimulatory mechanisms, as well as to identify the amino acid-sensing receptors involved in amino acid-stimulated GLP-1 release. Experiments were primarily based on isolated perfused
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