SML0010

LY-334370 hydrochloride hydrate

≥98% (HPLC), powder

• 别名: 4-Fluoro-N-[3-(1-methyl-4-piperidinyl)-1H-indol-5-yl]benzamide hydrochloride hydrate
• 经验公式（希尔记法）: C₂₁H₂₂FN₃O · HCl · xH₂O
• CAS号: 199673-74-0
• 分子量: 387.88 (anhydrous basis)
• MDL號碼: MFCD11519957
• 分類程式碼代碼: 12352202
• PubChem物質ID: 329825086
• NACRES: NA.77

属性

• 化驗: ≥98% (HPLC)
• 形狀: powder
• 顏色: white to tan
• 溶解度: H₂O: ≥5 mg/mL (warmed)
• 起源: Eli Lilly
• 儲存溫度: 2-8°C
• SMILES 字串: Cl.CN1CCC(CC1)c2c[nH]c3ccc(NC(=O)c4ccc(F)cc4)cc23
• InChI: 1S/C21H22FN3O.ClH/c1-25-10-8-14(9-11-25)19-13-23-20-7-6-17(12-18(19)20)24-21(26)15-2-4-16(22)5-3-15;/h2-7,12-14,23H,8-11H2,1H3,(H,24,26);1H
• InChI 密鑰: DGPDGAPZTPSHBL-UHFFFAOYSA-N

说明

應用

LY-334370 hydrochloride hydrate may be used to study 5-HT 1F-mediated cell signaling.

生化／生理作用

LY-334370 hydrochloride is a selective 5-HT1F receptor agonist.

LY-334370 modulates the transmission in the mouse trigeminal system and inhibits the neuronal responses within rat Sp5C by inhibiting c-Fos activation. It shows efficacy in aborting migraine attacks.

特點和優勢

This compound was developed by Eli Lilly. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

安全信息

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable