推荐产品
生物源
rabbit
品質等級
材料
colorless
無性繁殖
3I1C1, monoclonal
形狀
liquid
分子量
44 kDa
物種活性
human
濃度
1.18 mg/mL
技術
immunofluorescence: 1:50 - 1:200
western blot: 1:500 - 1:2000
顏色
colorless
同型
IgG
免疫原序列
KETLQRTDPPKTHMTHHPISDHEATLRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLPKPLTLRWEL
運輸包裝
wet ice
儲存溫度
−20°C
目標翻譯後修改
unmodified
基因資訊
human ... B(3106) , MHC class I (HLA-A(3105)
一般說明
HLA-A belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. Class I molecules play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen. They are expressed in nearly all cells. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon 1 encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domains, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exons 6 and 7 encode the cytoplasmic tail. Polymorphisms within exon 2 and exon 3 are responsible for the peptide binding specificity of each class one molecule. Typing for these polymorphisms is routinely done for bone marrow and kidney transplantation. Hundreds of HLA-A alleles have been described. [provided by RefSeq, Jul 2008]
免疫原
A synthetic peptide corresponding to a sequence within amino acids 200-300 of human MHC class I (HLA-A/B) (P04439).
PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
應用
WB, IF/ICC
儲存類別代碼
10 - Combustible liquids
水污染物質分類(WGK)
WGK 1
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