SAB5702978

Anti-FMRP Antibody, clone 4Y8I5, Rabbit Monoclonal

• 别名: FMRP, FRAXA, POF, POF1
• 分類程式碼代碼: 12352203

属性

• 生物源: rabbit
• 品質等級: 100
• 材料: colorless
• 無性繁殖: 4Y8I5, monoclonal
• 形狀: liquid
• 分子量: 70-80 kDa
• 物種活性: human, rat, rat
• 濃度: 0.5 mg/mL
• 技術: immunohistochemistry: 1:50 - 1:200; immunoprecipitation (IP): 1:50 - 1:200; western blot: 1:500 - 1:2000
• 顏色: colorless
• 同型: IgG
• 免疫原序列: MEELVVEVRGSNGAFYKAFVKDVHEDSITVAFENNWQPDRQIPFHDVRFPPPVGYNKDINESDEVEVYSRANEKEPCCWWLAKVRMIKGEFYVIEYAACD
• UniProt登錄號: Q06787
• 運輸包裝: wet ice
• 儲存溫度: −20°C
• 目標翻譯後修改: unmodified
• 基因資訊: human ... FMR1(2332)

说明

一般說明

The protein encoded by this gene binds RNA and is associated with polysomes. The encoded protein may be involved in mRNA trafficking from the nucleus to the cytoplasm. A trinucleotide repeat (CGG) in the 5' UTR is normally found at 6-53 copies, but an expansion to 55-230 repeats is the cause of fragile X syndrome. Expansion of the trinucleotide repeat may also cause one form of premature ovarian failure (POF1). Multiple alternatively spliced transcript variants that encode different protein isoforms and which are located in different cellular locations have been described for this gene. [provided by RefSeq, May 2010]

免疫原

A synthetic peptide corresponding to a sequence within amino acids 1-100 of human FMRP (Q06787).

PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

應用

WB, IHC, IP

安全信息

• 儲存類別代碼: 10 - Combustible liquids
• 水污染物質分類（WGK）: WGK 1