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Merck
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Key Documents

SAB5702752

Sigma-Aldrich

Anti-VAV3 Antibody, clone 9A10D8, Rabbit Monoclonal

别名:

vav 3 guanine nucleotide exchange factor

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About This Item

分類程式碼代碼:
12352203

生物源

rabbit

品質等級

材料

colorless

無性繁殖

9A10D8, monoclonal

形狀

liquid

分子量

98 kDa

物種活性

mouse, mouse

濃度

0.66 mg/mL

技術

immunohistochemistry: 1:50 - 1:200
western blot: 1:500 - 1:2000

顏色

colorless

同型

IgG

免疫原序列

TKESGEYAISIKYNNEAKHIKILTRDGFFHIAENRKFKSLMELVEYYKHHSLKEGFRTLDTTLQFPYKEPEHSAGQRGNRAGNSLLSPKVLGIAIARYDFC

UniProt登錄號

運輸包裝

wet ice

儲存溫度

−20°C

目標翻譯後修改

unmodified

基因資訊

human ... VAV3(10451)

一般說明

This gene is a member of the VAV gene family. The VAV proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements and transcriptional alterations. This gene product acts as a GEF preferentially for RhoG, RhoA, and to a lesser extent, RAC1, and it associates maximally with the nucleotide-free states of these GTPases. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]

免疫原

A synthetic peptide corresponding to a sequence within amino acids 700-800 of human VAV3 (Q9UKW4).
PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

應用

WB, IHC

儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 1


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