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Merck
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主要文件

SAB5702087

Sigma-Aldrich

Anti-Kinesin light chain 1 (KLC1) Antibody, clone 5C3P5, Rabbit Monoclonal

别名:

KLC1, KLC, KNS2, KNS2A, kinesin light chain 1

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About This Item

分類程式碼代碼:
12352203
NACRES:
NA.41

生物源

rabbit

品質等級

材料

colorless

無性繁殖

5C3P5, monoclonal

形狀

liquid

物種活性

human, rat, rat

濃度

0.67 mg/mL

技術

western blot: 1:500 - 1:2000

顏色

colorless

同型

IgG

免疫原序列

GGWYKACKVDSPTVTTTLKNLGALYRRQGKFEAAETLEEAAMRSRKQGLDNVHKQRVAEVLNDPENMEKRRSRESLNVDVVKYESGPDGGEEVSMSVEWNG

UniProt登錄號

運輸包裝

wet ice

儲存溫度

−20°C

目標翻譯後修改

unmodified

基因資訊

human ... KLC1(3831)

一般說明

Conventional kinesin is a tetrameric molecule composed of two heavy chains and two light chains, and transports various cargos along microtubules toward their plus ends. The heavy chains provide the motor activity, while the light chains bind to various cargos. This gene encodes a member of the kinesin light chain family. It associates with kinesin heavy chain through an N-terminal domain, and six tetratricopeptide repeat (TPR) motifs are thought to be involved in binding of cargos such as vesicles, mitochondria, and the Golgi complex. Thus, kinesin light chains function as adapter molecules and not motors per se. Although previously named ′kinesin 2′, this gene is not a member of the kinesin-2 / kinesin heavy chain subfamily of kinesin motor proteins. Extensive alternative splicing produces isoforms with different C-termini that are proposed to bind to different cargos; however, the full-length nature and/or biological validity of most of these variants have not been determined.

免疫原

A synthetic peptide corresponding to a sequence within amino acids 450-550 of human Kinesin light chain 1 (KLC1) (Q07866).
PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

應用

WB

儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 1


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