生物源
rabbit
品質等級
材料
colorless
無性繁殖
5C3P5, monoclonal
形狀
liquid
物種活性
human, rat, rat
濃度
0.67 mg/mL
技術
western blot: 1:500 - 1:2000
顏色
colorless
同型
IgG
免疫原序列
GGWYKACKVDSPTVTTTLKNLGALYRRQGKFEAAETLEEAAMRSRKQGLDNVHKQRVAEVLNDPENMEKRRSRESLNVDVVKYESGPDGGEEVSMSVEWNG
UniProt登錄號
運輸包裝
wet ice
儲存溫度
−20°C
目標翻譯後修改
unmodified
基因資訊
human ... KLC1(3831)
一般說明
Conventional kinesin is a tetrameric molecule composed of two heavy chains and two light chains, and transports various cargos along microtubules toward their plus ends. The heavy chains provide the motor activity, while the light chains bind to various cargos. This gene encodes a member of the kinesin light chain family. It associates with kinesin heavy chain through an N-terminal domain, and six tetratricopeptide repeat (TPR) motifs are thought to be involved in binding of cargos such as vesicles, mitochondria, and the Golgi complex. Thus, kinesin light chains function as adapter molecules and not motors per se. Although previously named ′kinesin 2′, this gene is not a member of the kinesin-2 / kinesin heavy chain subfamily of kinesin motor proteins. Extensive alternative splicing produces isoforms with different C-termini that are proposed to bind to different cargos; however, the full-length nature and/or biological validity of most of these variants have not been determined.
免疫原
A synthetic peptide corresponding to a sequence within amino acids 450-550 of human Kinesin light chain 1 (KLC1) (Q07866).
PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
應用
WB
儲存類別代碼
10 - Combustible liquids
水污染物質分類(WGK)
WGK 1
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