SAB5702066

Anti-Acetyl-p53-K382 Antibody, clone 0, Rabbit Monoclonal

• 别名: BCC7,LFS1,P53,TRP53,p53,TP53,BMFS5
• 分類程式碼代碼: 12352203
• NACRES: NA.46

属性

• 生物源: rabbit
• 品質等級: 100
• 材料: colorless
• 無性繁殖: 7Z8X9, monoclonal
• 形狀: liquid
• 分子量: 53 kDa
• 物種活性: mouse, mouse
• 濃度: 0.90 mg/mL
• 顏色: colorless
• 同型: IgG
• 免疫原序列: HKKLM
• UniProt登錄號: P04637
• 運輸包裝: wet ice
• 儲存溫度: −20°C
• 目標翻譯後修改: unmodified
• 基因資訊: human ... TP53(7157)

说明

一般說明

This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons from identical transcript variants (PMIDs: 12032546, 20937277).

免疫原

A synthetic acetylated peptide around K382 of human p53 (NP_000537.3).

PBS with 0.05% proclin300,50% glycerol,pH7.3.

應用

DB, WB

安全信息

• 象形圖: GHS07,GHS09
• 訊號詞: Warning
• 危險聲明: H317,H411
• 防範說明: P261 - P272 - P273 - P280 - P302 + P352 - P333 + P313
• 危險分類: Aquatic Chronic 2 - Skin Sens. 1
• 儲存類別代碼: 10 - Combustible liquids
• 水污染物質分類（WGK）: WGK 3