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Merck
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主要文件

SAB5701998

Sigma-Aldrich

Anti-CoA synthase Antibody, clone 7K2O6, Rabbit Monoclonal

别名:

COASY, DPCK, NBIA6, NBP, PPAT, UKR1, pOV-2, Coenzyme A synthase

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About This Item

分類程式碼代碼:
12352203
NACRES:
NA.46

生物源

rabbit

品質等級

材料

colorless

無性繁殖

7K2O6, monoclonal

形狀

liquid

分子量

62 kDa

物種活性

human

濃度

0.50 mg/mL

技術

western blot: 1:500 - 1:2000

顏色

colorless

同型

IgG

免疫原序列

RVCVIDAAVLLEAGWQNLVHEVWTAVIPETEAVRRIVERDGLSEAAAQSRLQSQMSGQQLVEQSHVVLSTLWEPHITQRQVEKAWALLQKRIPKTHQALD

UniProt登錄號

運輸包裝

wet ice

儲存溫度

−20°C

目標翻譯後修改

unmodified

基因資訊

human ... COASY(80347)

一般說明

Coenzyme A (CoA) functions as a carrier of acetyl and acyl groups in cells and thus plays an important role in numerous synthetic and degradative metabolic pathways in all organisms. In eukaryotes, CoA and its derivatives are also involved in membrane trafficking and signal transduction. This gene encodes the bifunctional protein coenzyme A synthase (CoAsy) which carries out the last two steps in the biosynthesis of CoA from pantothenic acid (vitamin B5). The phosphopantetheine adenylyltransferase domain of this bifunctional protein catalyzes the conversion of 4′-phosphopantetheine into dephospho-coenzyme A (dpCoA) while its dephospho-CoA kinase domain completes the final step by phosphorylating dpCoA to form CoA. Mutations in this gene are associated with neurodegeneration with brain iron accumulation (NBIA). Alternative splicing results in multiple isoforms.

免疫原

A synthetic peptide corresponding to a sequence within amino acids 465-564 of human CoA synthase (COASY) (Q13057).
PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

應用

WB

儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 1


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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