推荐产品
product name
抗AQP4 兔抗, 1 mg/mL, affinity isolated antibody
生物源
rabbit
品質等級
共軛
unconjugated
抗體表格
affinity isolated antibody
抗體產品種類
primary antibodies
無性繁殖
polyclonal
形狀
buffered aqueous glycerol solution
分子量
antigen predicted mol wt 35 kDa
物種活性
rat, human, mouse
濃度
1 mg/mL
技術
indirect immunofluorescence: suitable
western blot: suitable
NCBI登錄號
UniProt登錄號
運輸包裝
wet ice
儲存溫度
−20°C
目標翻譯後修改
unmodified
基因資訊
rat ... Aqp4(25293)
一般說明
水通道蛋白4（AQP4）在神经系统中表达。蛋白质的基因ID为25293。
特異性
检测 ~35 kDa。可检出较大的糖基化条带 ~50 kDa。
免疫原
C 末端肽
生化／生理作用
水通道蛋白 4 (AQP4) 在大鼠脑内发挥水通道的作用。
特點和優勢
完全放心地试用我们的抗体。如果抗体在您的申请的研究中不起作用，我们将全额退款或安排替代抗体。了解更多。
外觀
PH 7.4 PBS、50%甘油和0.09%叠氮化钠
免責聲明
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
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儲存類別代碼
10 - Combustible liquids
水污染物質分類（WGK）
WGK 1
閃點（°F）
Not applicable
閃點（°C）
Not applicable
S Ceccariglia et al.
Neuroscience, 274, 273-288 (2014-06-10)
Trimethyltin chloride (TMT) is a neurotoxicant producing neuronal degeneration and reactive astrogliosis in the mammalian central nervous system, especially the hippocampus. A previous magnetic resonance imaging investigation in TMT-treated rats evidenced dilation of lateral ventricles, also suggesting alterations in blood-brain
Alex J Smith et al.
Acta neuropathologica communications, 7(1), 74-74 (2019-05-10)
Redistribution of the water channel aquaporin-4 (AQP4) away from astrocyte endfeet and into parenchymal processes is a striking histological feature in mouse models of Alzheimer's disease (AD) and other neurological conditions with prominent astrogliosis. AQP4 redistribution has been proposed to
Gökhan Akdemir et al.
Neuroscience letters, 574, 70-75 (2014-04-11)
Astrocyte water channel aquaporin-4 (AQP4) facilitates water movement across the blood-brain barrier and into injured astrocytes. We previously showed reduced cytotoxic brain edema with improved neurological outcome in AQP4 knockout mice in water intoxication, infection and cerebral ischemia. Here, we
Jungo Kato et al.
Biochemical and biophysical research communications, 451(4), 562-567 (2014-08-16)
Aquaporin-4 (AQP4) is a water channel protein that is predominantly expressed in astrocytes in the CNS. The rapid water flux through AQP4 may contribute to electrolyte/water homeostasis and may support neuronal activities in the CNS. On the other hand, little
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