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Merck
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主要文件

SAB4700308

Sigma-Aldrich

Monoclonal Anti-HLA-G antibody produced in mouse

clone G233, purified immunoglobulin, buffered aqueous solution

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About This Item

分類程式碼代碼:
12352203
NACRES:
NA.41

生物源

mouse

共軛

unconjugated

抗體表格

purified immunoglobulin

抗體產品種類

primary antibodies

無性繁殖

G233, monoclonal

形狀

buffered aqueous solution

物種活性

human

濃度

1 mg/mL

技術

flow cytometry: suitable

同型

IgG2a

NCBI登錄號

UniProt登錄號

運輸包裝

wet ice

儲存溫度

2-8°C

目標翻譯後修改

unmodified

基因資訊

human ... HLA-G(3135)

一般說明

The antibody G233 recognizes several isoforms of HLA-G expressed in all populations of extravillous trophoblast (cell columns, interstitial trophoblast, endovascular trophoblast, placental bed giant cells). HLA-G belongs to the nonclassical MHC Class I molecules (MHC Class Ib). The antibody G233 has been found not to cross-react with any other MHC Class I antigens (HLA-A, -B, -C, -E, -F).

免疫原

HLA-A21/human beta2-microglobulin double transgenic mice were immunized with murine L cells transfected with both human beta2-microglobulin and HLA-G

應用

The reagent is designed for Flow Cytometry analysis. Suggested working dilution for Flow Cytometry is 5-10 μg/mL of sample. Indicated dilution is recommended starting point for use of this product. Working concentrations should be determined by the investigator.

特點和優勢

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

外觀

Solution in phosphate buffered saline, pH 7.4, with 15 mM sodium azide.

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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儲存類別代碼

10 - Combustible liquids

閃點(°F)

Not applicable

閃點(°C)

Not applicable


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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M J C Van Lierop et al.
Molecular human reproduction, 8(8), 776-784 (2002-08-01)
Human leukocyte antigen (HLA)-G, which is mainly expressed at the maternal-fetal interface, may play a role in the immune tolerance of the semi-allogenic fetus by the mother. Functional studies have shown that HLA-G is indeed a potential modulator of different
Jay M Bolnick et al.
Fertility and sterility, 102(1), 135-142 (2014-05-16)
To use trophoblast cells accumulating in the endocervical canal at the beginning of pregnancy for noninvasive prenatal testing. Prospective, double-blinded test for fetal gender. Academic medical center. Fifty-six women with singleton pregnancies at gestational age 5-20 weeks. Isolation of fetal
Nele Gao et al.
Arthritis & rheumatology (Hoboken, N.J.), 66(10), 2849-2861 (2014-06-20)
B cells with immunoregulatory properties (Breg cells) have been described in mice, but their role in the control of human immune responses is not well defined. We recently identified a human population of activated FSC(high) B cells that exhibited regulatory
Natasja Nielsen et al.
Immunology, 142(4), 581-593 (2014-03-29)
Rheumatoid arthritis (RA) is an autoimmune disease characterized by chronic inflammation and synovial hyperplasia leading to progressive joint destruction. Fibroblast-like synoviocytes (FLS) are central components of the aggressive, tumour-like synovial structure termed pannus, which invades the joint space and cartilage.

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