推荐产品
生物源
mouse
共軛
unconjugated
抗體表格
purified immunoglobulin
抗體產品種類
primary antibodies
無性繁殖
M38, monoclonal
形狀
buffered aqueous solution
物種活性
rabbit, human, feline
濃度
1 mg/mL
技術
flow cytometry: suitable
同型
IgG1
NCBI登錄號
UniProt登錄號
運輸包裝
wet ice
儲存溫度
2-8°C
目標翻譯後修改
unmodified
基因資訊
human ... CD81(975)
一般說明
Cluster of differentiation 81 (CD81) is expressed on the oocyte surface. It consists of five large helical segments and belongs to the tetraspanin family. The gene encoding this protein is localized on human chromosome 11p15.5.
The antibody M38 reacts with CD81, a 25 kDa member of the tetraspanin family, expressed on majority of cells.
免疫原
MOLT-4 (human T-ALL cell line)
應用
The reagent is designed for Flow Cytometry analysis. Suggested working dilution for Flow Cytometry is 1 μg/mL of sample. Indicated dilution is recommended starting point for use of this product. Working concentrations should be determined by the investigator.
生化／生理作用
Cluster of differentiation 81 (CD81) has a role in membrane organization, cell-cell interactions, cellular fusion and protein trafficking. It is also involved in receptor clustering and signaling. CD81 is overexpressed in cancers.
特點和優勢
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
外觀
Solution in phosphate buffered saline, pH 7.4, with 15 mM sodium azide.
免責聲明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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儲存類別代碼
10 - Combustible liquids
閃點（°F）
Not applicable
閃點（°C）
Not applicable
A role for CD81 and hepatitis C virus in hepatoma mobility.
Viruses, 6, 1454-1472 (2014)
CD81 as a tumor target.
Vences-Catalan F
Biochemical Society Transactions, 45, 531-535 (2017)
Oligomerization of the Tetraspanin CD81 via the Flexibility of Its ?-Loop.
Schmidt TH
Biophysical Journal, 110, 2463-2474 (2016)
A microarray-based DNA methylation study of
glioblastoma multiforme
Martinez R
Epigenetics, 4, 255-264 (2009)
Marguerite K McDonald et al.
Pain, 155(8), 1527-1539 (2014-05-06)
Exosomes, secreted microvesicles transporting microRNAs (miRNAs), mRNAs, and proteins through bodily fluids, facilitate intercellular communication and elicit immune responses. Exosomal contents vary, depending on the source and the physiological conditions of cells, and can provide insights into how cells and
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