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Merck
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主要文件

SAB4502822

Sigma-Aldrich

Anti-SMO antibody produced in rabbit

affinity isolated antibody

别名:

Gx protein, SMO

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About This Item

分類程式碼代碼:
12352203
NACRES:
NA.41

生物源

rabbit

共軛

unconjugated

抗體表格

affinity isolated antibody

抗體產品種類

primary antibodies

無性繁殖

polyclonal

形狀

buffered aqueous solution

分子量

antigen 86 kDa

物種活性

human, mouse, rat

濃度

~1 mg/mL

技術

ELISA: 1:10000
western blot: 1:500-1:1000

NCBI登錄號

UniProt登錄號

運輸包裝

wet ice

儲存溫度

−20°C

目標翻譯後修改

unmodified

基因資訊

human ... SMO(6608)

一般說明

Anti-SMO antibody detects endogenous levels of total SMO protein.
The SMO (smoothened) gene is mapped to human chromosome 7q32.1. It encodes a protein that belongs to the frizzled family of G protein-coupled receptors. It is a seven transmembrane protein and highly conserved.

免疫原

The antiserum was produced against synthesized peptide derived from human SMO.

Immunogen Range: 68-117

生化/生理作用

The SMO (smoothened) gene encodes a protein that mediates hedgehog signaling for embryonic development and to maintain tissue homeostasis. SMO participates in tumor cell proliferation.

特點和優勢

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

外觀

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

nwg

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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Inhibition of smoothened decreases proliferation of synoviocytes in rheumatoid arthritis.
Zhu SL
Cellular & Molecular Immunology, 14(2), 214-222 (2017)
Identification of Novel Smoothened Ligands Using Structure-Based Docking.
Lacroix C
PLoS ONE, 11(8), 1-20 (2016)
Epigenetics Offer New Horizons for Colorectal Cancer Prevention.
Schnekenburger M and Diederich M
Current Colorectal Cancer Reports, 8(1), 66-81 (2012)

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