推荐产品
生物源
rabbit
品質等級
共軛
unconjugated
抗體表格
affinity isolated antibody
抗體產品種類
primary antibodies
無性繁殖
polyclonal
形狀
buffered aqueous solution
分子量
antigen 33 kDa
物種活性
rat, mouse, human
濃度
~1 mg/mL
技術
ELISA: 1:5000
western blot: 1:500-1:1000
NCBI登錄號
UniProt登錄號
運輸包裝
wet ice
儲存溫度
−20°C
目標翻譯後修改
unmodified
基因資訊
human ... SFRP2(6423)
一般說明
Anti-SFRP2 Antibody detects endogenous levels of total SFRP2 protein.
The SFRP2 (secreted frizzled related protein 2) gene is mapped to human chromosome 4q31.3. It is found to be expressed in sclerotome.
免疫原
The antiserum was produced against synthesized peptide derived from human SFRP2.
Immunogen Range: 119-168
Immunogen Range: 119-168
生化/生理作用
SFRP2 (secreted frizzled related protein 2) promotes phosphorylation and retards the expression of nuclear β-catenin and inhibits the canonical Wnt signaling pathway. SFRP2 is known to enhance osteogenic differentiation in mesenchymal stem cells.
特點和優勢
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
外觀
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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儲存類別代碼
10 - Combustible liquids
水污染物質分類(WGK)
nwg
閃點(°F)
Not applicable
閃點(°C)
Not applicable
SFRP2 enhances the osteogenic differentiation of apical papilla stem cells by antagonizing the canonical WNT pathway.
Cellular & Molecular Biology Letters, 22:14, 1-14 (2017)
SHH-N upregulates Sfrp2 to mediate its competitive interaction with WNT1 and WNT4 in the somitic mesoderm.
Development, 127(1), 109-118 (2000)
A novel susceptibility locus for Hirschsprung's disease maps to 4q31.3-q32.3.
Journal of medical Genetics, 43(7), 1-6 (2006)
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