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生物源
rabbit
品質等級
共軛
unconjugated
抗體表格
affinity isolated antibody
抗體產品種類
primary antibodies
無性繁殖
polyclonal
形狀
buffered aqueous solution
分子量
antigen 60 kDa
物種活性
human, rat, mouse
濃度
~1 mg/mL
技術
ELISA: 1:5000
immunohistochemistry: 1:50-1:100
western blot: 1:500-1:1000
NCBI登錄號
UniProt登錄號
運輸包裝
wet ice
儲存溫度
−20°C
目標翻譯後修改
unmodified
基因資訊
human ... RELA(5970)
一般說明
Anti-NF-κB p65 Antibody detects endogenous levels of total NF-κB p65 protein.
RELA (v-rel avian reticuloendotheliosis viral oncogene homolog A), also known as nuclear factor κ-B (NF-κ-B) p65 subunit, codes for an important constituent of the NF-κB complex. The gene encoding it is localized on human chromosome 11q13.1. It is also referred as nuclear factor κB subunit 3 (NFκB3).
免疫原
The antiserum was produced against synthesized peptide derived from human NF-kappaB p65.
Immunogen Range: 247-296
Immunogen Range: 247-296
應用
Anti-NF-κB p65 antibody produced in rabbit is used in Western Blotting.
生化／生理作用
RELA (v-rel avian reticuloendotheliosis viral oncogene homolog A) or nuclear factor NF-κ-B p65 subunit participates in the nuclear factor κ-B (NFκB) signaling pathway. It also modulates inflammation. Alterations in the gene have been linked to schizophrenia and startle reactions.
特點和優勢
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
外觀
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
免責聲明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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儲存類別代碼
10 - Combustible liquids
水污染物質分類（WGK）
nwg
閃點（°F）
Not applicable
閃點（°C）
Not applicable
Reversal of cardiac and skeletal manifestations of Duchenne muscular dystrophy by cardiosphere-derived cells and their exosomes in mdx dystrophic mice and in human Duchenne cardiomyocytes.
Aminzadeh MA, et al.
bioRxiv, 128900-128900 (2017)
Bone morphogenetic protein-2 exhibits therapeutic benefits for osteonecrosis of the femoral head through induction of cartilage and bone cells.
Wang C, et al.
Experimental and Therapeutic Medicine (2018)
Genome-wide association analysis of soluble ICAM-1 concentration reveals novel associations at the NFKBIK, PNPLA3, RELA, and SH2B3 loci.
Pare G, et al.
PLoS Genetics, 7(4), e1001374-e1001374 (2011)
Variants of the RELA gene are associated with schizophrenia and their startle responses.
Hashimoto R, et al.
Neuropsychopharmacology, 36(9), 1921-1921 (2011)
Siwei Tan et al.
Cell death & disease, 12(5), 474-474 (2021-05-14)
Fas/Fas ligand (FasL)-mediated cell apoptosis involves a variety of physiological and pathological processes including chronic hepatic diseases, and hepatocytes apoptosis contributes to the development of liver fibrosis following various causes. However, the mechanism of the Fas/FasL signaling and hepatocytes apoptosis
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