SAB4501435

Anti-APBB2 antibody produced in rabbit

affinity isolated antibody

• 别名: Amyloid β A4 precursor protein-binding family B member 2, Fe65-like protein
• 分類程式碼代碼: 12352203
• NACRES: NA.41

属性

• 生物源: rabbit
• 共軛: unconjugated
• 抗體表格: affinity isolated antibody
• 抗體產品種類: primary antibodies
• 無性繁殖: polyclonal
• 形狀: buffered aqueous solution
• 分子量: antigen 83 kDa
• 物種活性: human, mouse
• 濃度: ~1 mg/mL
• 技術: ELISA: 1:40000; immunohistochemistry: 1:50-1:100; western blot: 1:500-1:1000
• NCBI登錄號: Q92870
• UniProt登錄號: Q92870
• 運輸包裝: wet ice
• 儲存溫度: −20°C
• 目標翻譯後修改: unmodified
• 基因資訊: human ... APBB2(323)

说明

一般說明

The gene APBB2 (amyloid β precursor protein binding family B member 2) is mapped to human chromosome 4p13.

免疫原

The antiserum was produced against synthesized peptide derived from human APBB2.

Immunogen Range: 471-520

生化／生理作用

The gene APBB2 (amyloid β precursor protein binding family B member 2), also referred to as FE65-like 1, encodes an adaptor protein that binds to the cytoplasmic domain of β-amyloid precursor protein (βAPP) and processes it to form β-amyloid (Aβ). Over-expression of APBB2 leads to an accumulation of Aβ in senile plaques seen in patients with Alzheimer′s disease (AD). Mutations in this gene have been associated with AD.

特點和優勢

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外觀

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

安全信息

• 儲存類別代碼: 10 - Combustible liquids
• 水污染物質分類（WGK）: nwg
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable