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Merck
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主要文件

SAB4501325

Sigma-Aldrich

Anti-MGLUR7 antibody produced in rabbit

affinity isolated antibody

别名:

GPRC1G, GRM7, MGLUR7, mGluR7, otein name Metabotropic glutamate receptor 7

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About This Item

分類程式碼代碼:
12352203
NACRES:
NA.41

生物源

rabbit

品質等級

共軛

unconjugated

抗體表格

affinity isolated antibody

抗體產品種類

primary antibodies

無性繁殖

polyclonal

形狀

buffered aqueous solution

分子量

antigen 102 kDa

物種活性

mouse, human, rat

濃度

~1 mg/mL

技術

ELISA: 1:20000
immunohistochemistry: 1:50-1:100
western blot: 1:500-1:1000

NCBI登錄號

UniProt登錄號

運輸包裝

wet ice

儲存溫度

−20°C

目標翻譯後修改

unmodified

基因資訊

human ... GRM7(2917)

相关类别

一般說明

Anti-MGLUR7 Antibody detects endogenous levels of total MGLUR7 protein.
MGLUR7 (glutamate metabotropic receptor 7) is coded by the glutamate receptor, metabotropic 7 (GRM7) gene. It is expressed in several parts of the central nervous system. mGluR7 is located in the presynaptic zone of the synaptic cleft of glutamatergic synapses. GRM7 gene is mapped to human chromosome 3p26. Anti-MGLUR7 Antibody detects endogenous levels of total MGLUR7 protein.

免疫原

The antiserum was produced against synthesized peptide derived from human mGluR7.

Immunogen Range: 866-915

生化/生理作用

The gene coding MGLUR7 (glutamate metabotropic receptor 7) is associated with autism. GRM7 participates in the initiation of glutamate receptor. It also participates in schizophrenia and bipolar disorder.

特點和優勢

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

外觀

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

nwg

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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Hemizygous deletion on chromosome 3p26. 1 is associated with heavy smoking among African American subjects in the COPDGene Study.
Begum F, et al.
PLoS ONE, 11(10), e0164134-e0164134 (2016)
A polymorphism of the metabotropic glutamate receptor mGluR7 (GRM7) gene is associated with schizophrenia.
Ohtsuki T, et al.
Schizophrenia Research, 101(1-3), 9-16 (2008)
Glutamate receptor, metabotropic 7 (GRM7) gene variations and susceptibility to autism: A case-control study.
Noroozi R, et al.
Autism Research : Official Journal of the International Society for Autism Research, 9(11), 1161-1168 (2016)

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