推荐产品
生物源
rabbit
品質等級
共軛
unconjugated
抗體表格
affinity isolated antibody
抗體產品種類
primary antibodies
無性繁殖
polyclonal
形狀
buffered aqueous solution
分子量
antigen 38 kDa
物種活性
mouse, human, rat
濃度
~1 mg/mL
技術
ELISA: 1:1000
immunofluorescence: 1:100-1:500
western blot: 1:500-1:1000
NCBI登錄號
UniProt登錄號
運輸包裝
wet ice
儲存溫度
−20°C
目標翻譯後修改
unmodified
基因資訊
human ... GPR18(2841)
一般說明
Anti-GPR18 antibody detects endogenous levels of total GPR18 protein. G protein-coupled receptor 18 (GPR18) is made up of 331 amino acids. GPR18 mRNA is located in murine spleen, bone marrow, thymus, lung and cerebellar tissue. This gene is located on human chromosome 13q32.
免疫原
The antiserum was produced against synthesized peptide derived from human GPR18.
Immunogen Range: 191-240
Immunogen Range: 191-240
生化／生理作用
G protein-coupled receptor 18 (GPR18) participates in cell migration and apoptosis. It modulates mitogen-activated protein kinases (MAPK) activity and immune stimulation.
特點和優勢
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
外觀
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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儲存類別代碼
10 - Combustible liquids
水污染物質分類（WGK）
nwg
閃點（°F）
Not applicable
閃點（°C）
Not applicable
Characterization of non-olfactory GPCRs in human sperm with a focus on GPR18
Flegel C, et al.
Scientific Reports, 6, 32255-32255 (2016)
D McHugh
British journal of pharmacology, 167(8), 1575-1582 (2012-05-09)
A review of what is presently known about the G protein coupled receptor GPR18 in terms of its expression and distribution, pharmacology and potential implications for central nervous system and endocannabinoid system signalling. LINKED ARTICLES This article is part of
Linda Console-Bram et al.
British journal of pharmacology, 171(16), 3908-3917 (2014-04-26)
GPR18 is a candidate cannabinoid receptor, but its classification as such is controversial. The rationale of the study presented herein was to consider the effects of N-arachidonoyl glycine (NAGly) and cannabinoids via differential G-protein coupled pathways, in addition to β-arrestin
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