SAB4300282
Anti-phospho-SYK (pTyr323) antibody produced in rabbit
affinity isolated antibody
别名:
Anti-DKFZp313N1010 antibody produced in rabbit, Anti-FLJ25043 antibody produced in rabbit, Anti-FLJ37489 antibody produced in rabbit, Anti-spleen tyrosine kinase antibody produced in rabbit
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所有图片(3)
About This Item
分類程式碼代碼:
12352203
NACRES:
NA.41
推荐产品
生物源
rabbit
共軛
unconjugated
抗體表格
affinity isolated antibody
抗體產品種類
primary antibodies
無性繁殖
polyclonal
形狀
buffered aqueous solution
分子量
~72 kDa
物種活性
human, rat, mouse
濃度
1 mg/mL
技術
immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:100
indirect immunofluorescence: 1:100-1:200
western blot: 1:500-1:1000
同型
IgG
免疫原序列
(N-P-YP-E-P)
NCBI登錄號
UniProt登錄號
運輸包裝
wet ice
儲存溫度
−20°C
目標翻譯後修改
phosphorylation (pTyr323)
基因資訊
human ... SYK(6850)
一般說明
Spleen tyrosine kinase (SYK) is a member of the non-receptor tyrosine kinase family. It is usually expressed in epithelial breast tissues and hematopoietic cells. The gene encoding it is localized on human chromosome 9q22.
免疫原
Peptide sequence around phosphorylation site of tyrosine 323 (N-P-Y(p)-E- P), according to the protein SYK.
生化／生理作用
Spleen tyrosine kinase (SYK) is a tumor suppressor gene that helps to prevent the development and metastasis of breast cancer cells. It participates in B-cell receptor signaling. The protein helps to phosphorylate the α-tubulin subunits of microtubules. SYK aids in the coupling of receptors for antigen-antibody complexes. It also modulates cell proliferation and differentiation.
特點和優勢
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
外觀
Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol
免責聲明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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儲存類別代碼
10 - Combustible liquids
水污染物質分類（WGK）
WGK 1
閃點（°F）
Not applicable
閃點（°C）
Not applicable
Inhibition of Spleen Tyrosine Kinase Potentiates Paclitaxel-Induced Cytotoxicity in Ovarian Cancer Cells by Stabilizing Microtubules.
Yu Y
Cancer Cell (2015)
Syk: a new player in the field of breast cancer
Zoe A
Breast Cancer Research (2000)
Novel SYK gene variations and changes in binding sites of miRs in breast cancer patients.
Faryal R
Cancer Biomarkers : Section A of Disease Markers (2016)
Syk Is Recruited to Stress Granules and Promotes Their Clearance through Autophagy.
Krisenko MO
The Journal of Biological Chemistry (2015)
Jiancheng Hu et al.
Journal of immunology (Baltimore, Md. : 1950), 193(1), 85-95 (2014-06-04)
Lysophospholipids have emerged as biologically important chemoattractants capable of directing lymphocyte development, trafficking, and localization. Lysophosphatidic acid (LPA) is a major lysophospholipid found systemically, and its levels are elevated in certain pathological settings, such as cancer and infections. In this
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