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Key Documents

SAB4300084

Sigma-Aldrich

Anti-phospho-RPS6KA1 (pThr348) antibody produced in rabbit

affinity isolated antibody

别名:

Anti-HU-1 antibody produced in rabbit, Anti-MAPKAPK1A antibody produced in rabbit, Anti-RSK antibody produced in rabbit, Anti-RSK1 antibody produced in rabbit, Anti-ribosomal protein S6 kinase, 90kDa, polypeptide 1 antibody produced in rabbit

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About This Item

MDL號碼:
分類程式碼代碼:
12352203
NACRES:
NA.41

生物源

rabbit

共軛

unconjugated

抗體表格

affinity isolated antibody

抗體產品種類

primary antibodies

無性繁殖

polyclonal

形狀

buffered aqueous solution

分子量

~90 kDa

物種活性

mouse, rat, human

濃度

1 mg/mL

技術

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:100
indirect immunofluorescence: 1:100-1:200
western blot: 1:500-1:1000

同型

IgG

免疫原序列

(S-R-TP-P-R)

NCBI登錄號

UniProt登錄號

運輸包裝

wet ice

儲存溫度

−20°C

目標翻譯後修改

phosphorylation (pThr348)

基因資訊

human ... RPS6KA1(6195)

免疫原

Peptide sequence around phosphorylation site of threonine 348 (S-R-T(p)-P-R), according to the protein RPS6KA1.

特點和優勢

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

標靶描述

Serine/threonine kinase that may play a role in mediating the growth-factor and stress induced activation of the transcription factor CREB.

外觀

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

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儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 1

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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Rong-Yu Liu et al.
Scientific reports, 10(1), 608-608 (2020-01-19)
Multiple kinases converge on the transcription factor cAMP response element-binding protein (CREB) to enhance the expression of proteins essential for long-term synaptic plasticity and memory. The p90 ribosomal S6 kinase (RSK) is one of these kinases, although its role is
Irem Ozkan-Dagliyan et al.
Cell reports, 31(11), 107764-107764 (2020-06-20)
We address whether combinations with a pan-RAF inhibitor (RAFi) would be effective in KRAS mutant pancreatic ductal adenocarcinoma (PDAC). Chemical library and CRISPR genetic screens identify combinations causing apoptotic anti-tumor activity. The most potent combination, concurrent inhibition of RAF (RAFi)
B Nadratowska-Wesolowska et al.
Oncogene, 33(40), 4823-4836 (2013-10-22)
FGFR1 (fibroblast growth factor receptor 1) regulates many key cellular responses including proliferation, migration and differentiation through activation of signaling pathways. Irregularities in FGFR1 signaling have been implicated in several pathological conditions, including human cancer. In order to discover novel

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