推荐产品
生物源
rabbit
共軛
unconjugated
抗體表格
affinity isolated antibody
抗體產品種類
primary antibodies
無性繁殖
polyclonal
形狀
buffered aqueous solution
物種活性
human, rat, mouse
技術
immunofluorescence: suitable
immunohistochemistry: suitable
indirect ELISA: suitable
western blot: suitable
NCBI登錄號
UniProt登錄號
運輸包裝
dry ice
儲存溫度
−20°C
目標翻譯後修改
unmodified
基因資訊
human ... RIPK1(8737)
一般說明
受体相互作用丝氨酸/苏氨酸蛋白激酶1(RIPK1)基因位于人染色体6p25.2上。属于RIPK家族。RIPK1是一种坏死性凋亡调节蛋白。它由N端激酶结构域、RIP同型相互作用基序和C端死亡结构域组成。
免疫原
RIPK1抗体通过人RIPK1氨基末端附近的15个氨基酸多肽免疫制取。
應用
兔抗-RIPK1抗体可用于：
- 蛋白质印迹
- 免疫细胞化学
- 免疫荧光
生化／生理作用
受体相互作用丝氨酸/苏氨酸蛋白激酶1(RIPK1)参与炎症信号转导和促存活(prosurvival)。还参与调节半胱天冬酶8介导的细胞凋亡。RIPK1在活化B细胞核因子κ-轻链增强子(NF-κB)和丝裂原激活蛋白(MAP)激酶的激活中发挥作用。其基因突变与损伤的固有和适应性免疫关联。还可导致极早发型炎症性肠病(VEO-IBDs)。
受体相互作用丝氨酸/苏氨酸蛋白激酶1(RIPK1)可调节细胞生存和死亡。还在炎症中起作用。
特點和優勢
完放心地使用我们的抗体。如果抗体在您的申请的研究中不起作用，我们将全额退款或安排替代抗体。了解更多信息。
聯結
可用封闭肽SBP3500420封闭该抗体作用。
外觀
以含有0.02%叠氮化钠的PBS形式提供。
免責聲明
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的人类或动物食用或应用。
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儲存類別代碼
10 - Combustible liquids
水污染物質分類（WGK）
WGK 2
閃點（°F）
Not applicable
閃點（°C）
Not applicable
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