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Merck
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主要文件

SAB3500065

Sigma-Aldrich

Anti-Seasonal H1N1 Neuraminidase antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

别名:

Anti-Flu N1, Anti-Influenza N1, Anti-NA, Anti-Seasonal Influenza A (H1N1) Neuraminidase

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About This Item

分類程式碼代碼:
12352203
NACRES:
NA.41
共軛:
unconjugated
application:
ELISA (i)
無性繁殖:
polyclonal
物種活性:
viral
citations:
技術:
indirect ELISA: suitable

生物源

rabbit

品質等級

共軛

unconjugated

抗體表格

affinity isolated antibody

抗體產品種類

primary antibodies

無性繁殖

polyclonal

形狀

buffered aqueous solution

物種活性

viral

技術

indirect ELISA: suitable

NCBI登錄號

UniProt登錄號

運輸包裝

dry ice

儲存溫度

−20°C

目標翻譯後修改

unmodified

相关类别

免疫原

Neuraminidase antibody was raised against a synthetic peptide from the seasonal influenza (H1N1) Neuraminidase protein. This antibody is a cognate pair with product SAB3500066.

特點和優勢

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

標靶描述

Influenza A virus is a major public health threat, killing more than 30,000 people per year in the USA (1). In early 2009, a novel swine-origin influenza A (H1N1) virus was identified in specimens obtained from patients in Mexico and the United States (2). The virus spread quickly around the world and on June 11, 2009, the World Health Organization declared it a pandemic (3). Influenza A virus has one of sixteen possible Hemagglutinin (HA) surface proteins and one of nine possible neuraminidase (NA) surface proteins. The Hemagglutinin protein facilitates viral attachment while neuraminidase is involved in viral release. These proteins also elicit immune responses that prevent infection or independently reduce viral replication. The genetic make-up of this swine flu virus is unlike any other: it is an H1N1 strain that combines a triple assortment first identified in 1998 including human, swine, and avian influenza with two new pig H3N2 virus genes from Eurasia, themselves of recent human origin (4). The distinct antigenic properties of the new swine influenza virus compared with seasonal influenza A (H1N1) virus suggest that human immunity against new swine influenza virus is limited, although the age distribution of reported cases suggests some degree of protection in older age groups (5). This antibody is specific for Neuraminidase from the seasonal influenza (H1N1) and will not recognize the corresponding Neuraminidase sequence from the swine-origin influenza virus (A/California/14/2009 (H1N1)).

聯結

The action of this antibody can be blocked using blocking peptide SBP3500065.

外觀

Supplied at approx. 1 mg/mL in phosphate buffered saline containing 0.02% sodium azide.

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儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 2

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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