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生物源
goat
品質等級
共軛
unconjugated
抗體表格
affinity isolated antibody
抗體產品種類
primary antibodies
無性繁殖
polyclonal
形狀
buffered aqueous solution
物種活性
human, mouse, rat, canine
技術
immunohistochemistry: suitable
indirect ELISA: suitable
western blot: suitable
UniProt登錄號
運輸包裝
dry ice
儲存溫度
−20°C
目標翻譯後修改
unmodified
基因資訊
human ... MYB(4602)
一般說明
Myeloblastosis (MYB) proto-oncogene, transcription factor (MYB) gene codes for a transcriptional activator, Myb-nuclear factor 1 B-type (MYB-NFIB), and is located on human chromosome 6q23.3.
免疫原
Peptide with sequence C-QRHYNDEDPEKEKR from the internal region of the protein sequence according to NP_005366.2.
生化／生理作用
Myeloblastosis (MYB) proto-oncogene, transcription factor (MYB) plays a key role in modulating various cellular genes that participates in the proliferation, differentiation, and apoptosis of cells. This protein promotes the development and metastasis of salivary adenoid cystic carcinoma (SACC). MYB plays ah role in initiating and maintaining acute leukemias. It participates in pancreatic cancer, prostate cancer, colorectal cancer, and breast cancer (BC).
特點和優勢
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
外觀
Supplied at 0.5 mg/mL in Tris saline with 0.02% sodium azide and 0.5% bovine serum albumin.
免責聲明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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訊號詞
Warning
危險聲明
危險分類
Eye Irrit. 2 - Skin Irrit. 2
儲存類別代碼
10 - Combustible liquids
水污染物質分類（WGK）
WGK 2
閃點（°F）
Not applicable
閃點（°C）
Not applicable
Ren-Ming Yang et al.
Oncogene, 38(26), 5239-5249 (2019-04-12)
Over 70% of human breast cancers are estrogen receptor-positive (ER+), most of which express MYB. In these and other cell types, the MYB transcription factor regulates the expression of many genes involved in cell proliferation, differentiation, tumorigenesis, and apoptosis. So
Li-Hua Xu et al.
International journal of oncology, 54(5), 1579-1590 (2019-03-22)
The incidence of recurrent t(6;9) translocation of the MYB proto‑oncogene to NFIB (the gene that encodes nuclear factor 1 B‑type) in adenoid cystic carcinoma (ACC) tumour tissues is high. However, MYB [the gene that encodes transcriptional activator Myb (MYB)] overexpression is more common
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