SAB2500307
Anti-DGAT1 antibody produced in goat
affinity isolated antibody, buffered aqueous solution
别名:
Anti-ACAT related gene product 1, Anti-ARGP1, Anti-Acyl coenzyme A:cholesterol acyltransferase related gene 1, Anti-DGAT, Anti-Diacylglycerol O-acyltransferase homolog 1
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About This Item
推荐产品
生物源
goat
品質等級
共軛
unconjugated
抗體表格
affinity isolated antibody
抗體產品種類
primary antibodies
無性繁殖
polyclonal
形狀
buffered aqueous solution
物種活性
human, rat, canine, mouse
技術
immunohistochemistry: suitable
indirect ELISA: suitable
western blot: suitable
UniProt登錄號
運輸包裝
dry ice
儲存溫度
−20°C
目標翻譯後修改
unmodified
基因資訊
human ... DGAT1(8694)
一般說明
Diacylglycerol O-acyltransferase 1 (DGAT1) is a 500kDa, hydrophobic protein, which is highly expressed in the skin, mammary gland, adipose tissue, small intestine and testis. The gene encoding it is localized on human chromosome 8q24.3.
免疫原
Peptide with sequence C-QNSMKPFKDMDYS from the internal region of the protein sequence according to NP_036211.1.
應用
Anti-DGAT1 antibody produced in goat has been used in Western blotting.
生化/生理作用
Diacylglycerol O-acyltransferase 1 (DGAT1) has a role in the biosynthesis of triglycerides. Mutations in the gene have been linked to congenital diarrhea and protein-losing enteropathy. DGAT1 is also associated with metabolic disorders like diabetes and obesity.
特點和優勢
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
外觀
Supplied at 0.5 mg/mL in Tris saline with 0.02% sodium azide and 0.5% bovine serum albumin.
免責聲明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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儲存類別代碼
10 - Combustible liquids
水污染物質分類(WGK)
WGK 2
閃點(°F)
Not applicable
閃點(°C)
Not applicable
The triacylglycerol synthesis enzyme DGAT1 also catalyzes the synthesis of diacylglycerols, waxes, and retinyl esters
Journal of Lipid Research (2005)
Molecular pharmacology, 81(2), 228-238 (2011-11-05)
Synthetic rexinoids effectively suppress both estrogen receptor-positive and estrogen receptor-negative mammary tumors in animal models, which makes them prime candidates for a novel class of cancer-preventive agents. When used in combination with chemotherapy for non-small-cell lung cancer, the rexinoid bexarotene
Identification and characterization of a novel DGAT1 missense mutation associated with congenital diarrhea.
Journal of Lipid Research (2017)
Prolonged silencing of diacylglycerol acyltransferase-1 induces a dedifferentiated phenotype in human liver cells.
Journal of Cellular and Molecular Medicine (2016)
Cancer-Preventive Rexinoid Modulates Neutral Lipid Contents of Mammary Epithelial Cells through a Peroxisome Proliferator-Activated Receptor ?-Dependent Mechanism
Molecular Pharmacology (2012)
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