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Merck
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Key Documents

SAB2106779

Sigma-Aldrich

Anti-VAMP7 antibody produced in rabbit

affinity isolated antibody

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About This Item

分類程式碼代碼:
12352203
NACRES:
NA.41

生物源

rabbit

品質等級

共軛

unconjugated

抗體表格

affinity isolated antibody

抗體產品種類

primary antibodies

無性繁殖

polyclonal

形狀

buffered aqueous solution

分子量

25 kDa

物種活性

mouse, bovine, rabbit, guinea pig, sheep, horse, dog, human, rat

濃度

0.5 mg - 1 mg/mL

技術

western blot: suitable

NCBI登錄號

UniProt登錄號

運輸包裝

wet ice

儲存溫度

−20°C

目標翻譯後修改

unmodified

基因資訊

human ... VAMP7(6845)
mouse ... Vamp7(20955)

免疫原

The immunogen for anti-VAMP7 antibody: synthetic peptide derected towards the C terminal of human VAMP7

生化/生理作用

Vamp7 is involved in the targeting and/or fusion of transport vesicles to their target membrane during transport of proteins from the early endosome to the lysosome. Vamp7 is required for heterotypic fusion of late endosomes with lysosomes and homotypic lysosomal fusion.Vamp7 is required for calcium regulated lysosomal exocytosis. Vamp7 is involved in the export of chylomicrons from the endoplasmic reticulum to the cis Golgi.Vamp7 is required for exocytosis of mediators during eosinophil and neutrophil degranulation, and target cell killing by natural killer cells. Vamp7 is also required for focal exocytosis of late endocytic vesicles during phagosome formation.

序列

Synthetic peptide located within the following region: DELKGIMVRNIDLVAQRGERLELLIDKTENLVDSSVTFKTTSRNLARAMC

外觀

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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