SAB1406356
Anti-PYCR1 antibody produced in mouse
purified immunoglobulin, buffered aqueous solution
别名:
P5C, P5CR, PIG45, PP222, PYCR
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所有图片(3)
About This Item
分類程式碼代碼:
12352203
NACRES:
NA.41
共軛:
unconjugated
application:
IF
WB
WB
無性繁殖:
polyclonal
物種活性:
human
citations:
5
技術:
indirect immunofluorescence: suitable
western blot: 1 μg/mL
western blot: 1 μg/mL
推荐产品
生物源
mouse
品質等級
共軛
unconjugated
抗體表格
purified immunoglobulin
抗體產品種類
primary antibodies
無性繁殖
polyclonal
形狀
buffered aqueous solution
分子量
antigen ~33.4 kDa
物種活性
human
技術
indirect immunofluorescence: suitable
western blot: 1 μg/mL
NCBI登錄號
UniProt登錄號
運輸包裝
dry ice
儲存溫度
−20°C
目標翻譯後修改
unmodified
基因資訊
human ... PYCR1(5831)
一般說明
Pyrroline-5-carboxylate reductase 1 (PYCR1) is a housekeeping gene.The gene is located on human chromosome 17q25.3.
免疫原
PYCR1 (NP_008838.2, 1 a.a. ~ 319 a.a) full-length human protein.
Sequence
MSVGFIGAGQLAFALAKGFTAAGVLAAHKIMASSPDMDLATVSALRKMGVKLTPHNKETVQHSDVLFLAVKPHIIPFILDEIGADIEDRHIVVSCAAGVTISSIEKKLSAFRPAPRVIRCMTNTPVVVREGATVYATGTHAQVEDGRLMEQLLSSVGFCTEVEEDLIDAVTGLSGSGPAYAFTALDALADGGVKMGLPRRLAVRLGAQALLGAAKMLLHSEQHPGQLKDNVSSPGGATIHALHVLESGGFRSLLINAVEASCIRTRELQSMADQEQVSPAAIKKTILDKVKLDSPAGTALSPSGHTKLLPRSLAPAGKD
Sequence
MSVGFIGAGQLAFALAKGFTAAGVLAAHKIMASSPDMDLATVSALRKMGVKLTPHNKETVQHSDVLFLAVKPHIIPFILDEIGADIEDRHIVVSCAAGVTISSIEKKLSAFRPAPRVIRCMTNTPVVVREGATVYATGTHAQVEDGRLMEQLLSSVGFCTEVEEDLIDAVTGLSGSGPAYAFTALDALADGGVKMGLPRRLAVRLGAQALLGAAKMLLHSEQHPGQLKDNVSSPGGATIHALHVLESGGFRSLLINAVEASCIRTRELQSMADQEQVSPAAIKKTILDKVKLDSPAGTALSPSGHTKLLPRSLAPAGKD
生化／生理作用
Pyrroline-5-carboxylate reductase 1 (PYCR1) acts as a prognostic biomarker for breast cancer.Mutations in this gene affects mitochondrial function and is associated with connective tissue disorder cutis laxa.It helps in cell metabolism.This protein catalyses the conversion of 1-piperideine-6-carboxylate (P6C) into pipecolic acid.
外觀
Solution in phosphate buffered saline, pH 7.4
免責聲明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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儲存類別代碼
10 - Combustible liquids
水污染物質分類（WGK）
WGK 1
閃點（°F）
Not applicable
閃點（°C）
Not applicable
Improving the prediction accuracy in classification using the combined data sets by ranks of gene expressions
Kim, Ki, et al.
BMC Bioinformatics, 9(1), 283-283 (2008)
Human pyrroline-5-carboxylate reductase (PYCR1) acts on Delta 1-piperideine-6-carboxylate generating L-pipecolic acid
Struys,, et al.
Journal of inherited metabolic disease, 37(3), 327-332 (2014)
Resolving the cofactor binding site in the proline biosynthetic enzyme human pyrroline-5-carboxylate reductase 1
Christen, et al.
The Journal of Biological Chemistry, jbc-M117 (2017)
Knockdown of PYCR1 inhibits cell proliferation and colony formation via cell cycle arrest and apoptosis in prostate cancer
Zeng, Te, et al.
Medical Oncology (Northwood, London, England), 34(2), 27-27 (2017)
Resolving the cofactor binding site in the proline biosynthetic enzyme human pyrroline-5-carboxylate reductase 1
Christen, et al.
Test, jbc-M117 (2017)
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