SAB1300449

Anti-DGKZ (C-term) antibody produced in rabbit

IgG fraction of antiserum, buffered aqueous solution

• 别名: Anti-ζ, Anti-DAG kinase ζ, Anti-DGK-ζ, Anti-Diacylglycerol kinase, Anti-Diglyceride kinase
• 分類程式碼代碼: 12352203
• NACRES: NA.41

属性

• 生物源: rabbit
• 品質等級: 100
• 共軛: unconjugated
• 抗體表格: IgG fraction of antiserum
• 抗體產品種類: primary antibodies
• 無性繁殖: polyclonal
• 形狀: buffered aqueous solution
• 物種活性: human
• 技術: immunohistochemistry: 1:50-1:100; indirect ELISA: 1:1000; western blot: 1:100-1:500
• NCBI登錄號: NP_963290
• UniProt登錄號: Q13574
• 運輸包裝: dry ice
• 儲存溫度: −20°C
• 目標翻譯後修改: unmodified
• 基因資訊: human ... DGKZ(8525)

说明

一般說明

Diacylglycerol kinase zeta ζ (DGKZ) belongs to the diacylglycerol kinase family. It is expressed in the central nervous system and comprises a nuclear localization signal, ankyrin repeats, and a PDZ-binding motif. DGKZ gene is localized on human chromosome 11p11.2.

免疫原

DGKZ (NP_963290, 994-1029)
This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human DGKZ.

生化／生理作用

Diacylglycerol kinase zeta ζ (DGKZ) plays a key role in brain development. It mediates the conversion of diacylglycerol to phosphatidic acid. Elevated DGKZ levels is observed in human metastatic colon cancer. DGKZ protein defects are implicated in osteogenesis imperfecta (OI) leading to a phenotype characterized by fractures in utero and after birth, callus formation, and beaded ribs. DGKZ also regulates bone homeostasis. Knockdown of the DGKζ gene leads to cell cycle arrest and apoptosis in glioma cells.

外觀

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全信息

• 儲存類別代碼: 10 - Combustible liquids
• 水污染物質分類（WGK）: nwg
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable